Silent Adrenal Pheochromocytoma Coexistent with Corticomedullary Hyperplasia: A Case Incidentally Discovered
  • Luigi Petramala
    Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Federica Olmati
    Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Antonio Concistrè
    Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Vincenza Saraceno
    Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Gino Iannucci
    Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Antonio Ciardi
    Department of Surgery “Pietro Valdoni”, University “Sapienza”, Rome
  • Giorgio De Toma
    Department of Surgery “Pietro Valdoni”, University “Sapienza”, Rome
  • Claudio Letizia
    Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome http://orcid.org/0000-0003-4397-0624

Keywords

Adrenal Incidentaloma, Subclinical Hypercortisolism, Pheochromocytoma, adrenal hyperplasia

Abstract

Introduction: Pheochromocytoma (PHEO) is a rare catecholamine-producing tumour arising from chromaffin cells in the sympatho-adrenal system, and can present as asymptomatic adrenal incidentaloma (AI).

Patient: We describe the case of a 61-year-old woman with a right adrenal mass incidentally discovered, who was biochemically characterized with subclinical hypercortisolism (SH). The patient was scheduled for adrenalectomy because of increasing seizure of the right adrenal gland with a haemorrhagic and focal pseudocystic appearance macroscopically, incidental histological and immunohistochemical PHEO, and micronodular cortico-adrenal hyperplasia.

Discussion: This report describes a rare case of incidental non-functioning PHEO coexisting with corticomedullary hyperplasia and SH.

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    Published: 2017-10-06
    Issue: Vol. 4 No. 10 (view)

    How to cite:
    1.
    Petramala L, Olmati F, Concistrè A, Saraceno V, Iannucci G, Ciardi A, De Toma G, Letizia C. Silent Adrenal Pheochromocytoma Coexistent with Corticomedullary Hyperplasia: A Case Incidentally Discovered. EJCRIM 2017;4 doi:10.12890/2017_000714.