Acute Colchicine-induced Neuromyopathy in a Patient Treated with Atorvastatin and Clarithromycin
KeywordsColchicine, neuromyopathy, atorvastatin, clarithromycin
Neuromyopathy is a rare side effect of chronic colchicine therapy, especially without renal impairment. Drugs interacting with colchicine metabolism through CYP3A4 can accelerate accumulation and toxicity. We describe a case of an interaction between atorvastatin, clarithromycin and colchicine resulting in acute neuromyopathy.
Issue: Vol 6 No 3 (view)