Ocular Melanoma Presenting as Masquerade Syndrome

  • Sara Simões Macedo Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal http://orcid.org/0000-0001-5152-7505
  • Mónica Teixeira Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal
  • Andreia Correia Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal
  • António Novais Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal
  • Cátia Cabral Department of Internal Medicine, Hospital Trofa Vila Real, Vila Real, Portugal

Keywords

Ocular melanoma, intraocular haemorrhage, endogenous endophthalmitis, masquerade syndrome, metastasis

Abstract

A masquerade syndrome is an ophthalmological entity where a neoplasm mimics an inflammatory condition. Ocular melanoma (chiefly uveal) may present with symptoms suggestive of intraocular inflammation such as endogenous endophthalmitis. Ocular melanoma is most commonly found in middle-aged and older caucasian patients. One-third of all uveal melanoma cases present asymptomatically. Early diagnosis facilitates treatment before ocular melanoma reaches metastatic stage IV. Current therapy options for stage IV patients are palliative care and clinical trial participation.eed for clinicians to be aware of rare metastases at the time of diagnosis.

References

  • Turgut B. Ocular masquerade syndrome. Adv Ophthalmol Vis Syst 2018;8:148-149.

  • Pham CM, Kalyam K, Smith BT, Floyd J, Holds JB. Acute angle closure precipitated by hemorrhage and necrosis of a large uveal melanoma in the setting of systemic immunomodulatory therapy. Ocul Oncol Pathol 2017;3(4):254–258.

  • Oellers P, Wolkow N, Jakobiec FA, Kim IK. Hemorrhagic choroidal melanoma. Am J Ophthalmol Case Rep 2018;10:105–107.

  • Krantz BA, Dave N, Komatsubara KM, Marr BP, Carvajal RD. Uveal melanoma: epidemiology, etiology, and treatment of primary disease. Clin Ophthalmol 2017;11:279–289.

  • Singh AD, Medina CA, Singh N, Aronow ME, Biscotti CV, Triozzi PL. Fine-needle aspiration biopsy of uveal melanoma: outcomes and complications. Br J Ophthalmol 2016;100(4):456–462.
  • Published: 2019-07-01

    Issue: Vol 6 No 7 (view)

    Section: Articles

    How to cite:
    Macedo, S., Teixeira, M., Correia, A., Novais, A., & Cabral, C. (2019). Ocular Melanoma Presenting as Masquerade Syndrome. European Journal of Case Reports in Internal Medicine, 6(7). https://doi.org/https://doi.org/10.12890/2019_001118

    Most read articles by the same author(s)