Hiccups and Inappropriate ADH Secretion Syndrome as Presentations of Tick-Borne Disease
  • Andrea Da Porto
    Clinica Medica, University of Udine, Udine, Italy
  • Michele Battellino
    Internal Medicine Department, Tolmezzo Hospital, Tolmezzo, Italy
  • Gianluca Colussi
    Clinica Medica, University of Udine, Udine, Italy
  • Vito Di Piazza
    Internal Medicine Department, Tolmezzo Hospital, Tolmezzo, Italy
  • Leonardo Sechi
    Clinica Medica, University of Udine, Udine, Italy

Keywords

Hyponatremia, hiccups, tick-borne encephalitis, Lyme disease

Abstract

Tick-borne diseases (Lyme disease and tick-borne encephalitis) are becoming a major public health concern. Rapid and correct diagnosis is crucial for complicated cases but is often delayed because of low suspicion or unusual clinical presentation. In this paper the authors describe two atypical presentations of Lyme disease and tick-borne encephalitis in order to help clinicians resolve diagnostic challenges.

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References

  • Sprong H, Hofhuis A, Gassner F, Takken W, Jacobs F, van Vliet AJ. Circumstantial evidence for an increase in the total number and activity of Borrelia-infected Ixodes ricinus in the Netherlands. Parasit Vectors 2012;5(1):294.

  • Dubrey SW, Bhatia A, Woodham S, Rakowicz W. Lyme disease in the United Kingdom. Postgrad Med J 2014;90(1059):33–42.

  • Trájer A, Bobvos J, Páldy A, Krisztalovics K. Association between incidence of Lyme disease and spring-early summer season temperature changes in Hungary--1998-2010. Ann Agric Environ Med 2013;20(2):245–251.

  • Septfons A, Goronflot T, Jaulhac B, Roussel V, De Martino S, Guerreiro S, et al. Epidemiology of Lyme borreliosis through two surveillance systems: the national Sentinelles GP network and the national hospital discharge database, France, 2005 to 2016. Euro Surveill 2019;24(11).

  • Hellenbrand W, Kreusch T, Böhmer MM, Wagner-Wiening C, Dobler G, Wichmann O, et al. Epidemiology of tick-borne encephalitis (TBE) in Germany, 2001–2018. Pathogens 2019;8:42.

  • Shamin EA, Shamin SA, Liss G, Nylen E, Pincus JH, Yepes M. Constipation heralding neuroborreliosis: an atypical tale of 2 patients. Arch Neurol 2005;62:671–673.

  • Weller M, Stevens A, Sommer N, Wiethölter H, Dichgans J. Cerebrospinal fluid interleukins, immunoglobulins, and fibronectin in neuroborreliosis. Arch Neurol 1991;48:837–841.

  • Perkins MP, Shumway N, Jackson WL Jr. Lyme neuroborreliosis presenting as the syndrome of inappropriate antidiuretic hormone secretion. MedGenMed 2006;8(3):71.

  • Sugimoto T, Takeda N, Yamakawa I, Kawai H, Tanaka Y, Sakaguchi M, et al. Intractable hiccup associated with aseptic meningitis in a patient with systemic lupus erythematosus. Lupus 2008;17(2):152–153.

  • Hemachudha T, Phanthumchinda K, Indrakoses A, Wilde HG. Intractable hiccups (singultus) as presenting manifestation of Japanese encephalitis. J Med Assoc Thai 1984;67(11):621–623.

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    Published: 2019-07-24
    Issue: Vol 6 No 8 (view)

    How to cite:
    1.
    Da Porto A, Battellino M, Colussi G, Di Piazza V, Sechi L. Hiccups and Inappropriate ADH Secretion Syndrome as Presentations of Tick-Borne Disease. EJCRIM 2019;6 doi:10.12890/2019_001188.