Immunoglobulin Treatment in Severe Ovarian Hyperstimulation Syndrome
  • Gemma Grau
    Department of Internal Medicine, Fundació Mútua de Terrassa, Terrassa, Spain
  • Oriol Giménez
    Department of Obstetrics and Gynecology, Fundació Mútua de Terrassa, Terrassa, Spain
  • Nuria Pons
    Department of Obstetrics and Gynecology, Fundació Mútua de Terrassa, Terrassa, Spain
  • Mireia Cairó
    Department of Internal Medicine, Fundació Mútua de Terrassa, Terrassa, Spain
  • Pedro Almagro
    Department of Internal Medicine, Fundació Mútua de Terrassa, Terrassa, Spain

Keywords

Severe ovarian hyperstimulation syndrome, immunoglobulins

Abstract

A 32-year-old woman undergoing an in vitro fertilization program was admitted to our hospital with the diagnosis of severe ovarian hyperstimulation syndrome (OHSS). Transvaginal ultrasonography showed two gestational sacs. Treatment with fluid restriction, serum albumin and intravenous furosemide was started, and repeated thoracentesis and paracenteses were performed. In the absence of clinical improvement, the patient was transferred to the intensive care unit and a therapeutic abortion was suggested. Due to the similarities between OHSS and idiopathic systemic capillary leak syndrome, we offered the patient compassionate treatment with intravenous immunoglobulins.
After administration, the patient showed rapid improvement and we were able to suspend intravenous furosemide and serum albumin. She was discharged, and pregnancy has continued normally to date.

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References

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    Published: 2019-10-02
    Issue: Vol 6 No 10 (view)


    How to cite:
    1.
    Grau G, Giménez O, Pons N, Cairó M, Almagro P. Immunoglobulin Treatment in Severe Ovarian Hyperstimulation Syndrome. EJCRIM 2019;6 doi:10.12890/2019_001253.