Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association
  • Elisabete Pereira Coelho
    Unidade de Cuidados Intensivos Polivalente, Hospital de Braga, Braga, Portugal
  • Ana Rita Matos
    Serviço de Medicina Interna, Hospital de Braga, Braga, Portugal
  • Sofia Caridade
    Serviço de Medicina Interna, Hospital de Braga, Braga, Portugal


Autoimmune hepatitis, systemic sclerosis, alcoholic hepatitis


A woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted. Laboratory investigations revealed hyperbilirubinemia, hypergammaglobulinemia and positive anti-smooth muscle antibodies. Histologic examination of the skin was compatible with scleroderma. Histologic examination of the liver was suggestive of autoimmune and alcoholic hepatitis.



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    Published: 2019-12-13
    Issue: Vol 6 No 12 (view)

    How to cite:
    Coelho EP, Matos AR, Caridade S. Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association. EJCRIM 2019;6 doi:10.12890/2019_001352.

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