Palmoplantar Pustulosis-like Eruption Induced by Baricitinib for Treatment of Rheumatoid Arthritis
  • Dimitra Koumaki
    Dermatology Department, University Hospital of Heraklion, Crete, Greece
  • Vasiliki Koumaki
    Microbiology Department, Medical School of Athens, Athens , Greece
  • George Bertsias
    Rheumatology Department, University Hospital of Heraklion, Crete, Greece
  • Eleni Lagoudaki
    Pathology Department, University Hospital of Heraklion, Crete, Greece
  • George Bertsias
    Rheumatology Department, University Hospital of Heraklion, Crete, Greece

Keywords

Palmoplantar pustulosis, baricitinib, rheumatoid arthritis, cutaneous side effects

Abstract

Objectives: Baricitinib is an orally active Janus kinase (JAK) inhibitor used in the treatment of moderate to severe rheumatoid arthritis (RA).
Materials and methods: Here, we report the case of a 56-year-old Caucasian male diagnosed with RA who developed palmoplantar pustulosis (PPP) while being treated with baricitinib.
Results: The patient’s PPP resolved after discontinuation of baricitinib and recurred when this was restarted. Based on causality assessment, it was considered a drug-induced PPP. Conclusion: To the authors’ knowledge, this is the first case of baricitinib-induced PPP.

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References

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    Published: 2019-12-19
    Issue: 2020: Vol 7 No 1 (view)

    How to cite:
    1.
    Koumaki D, Koumaki V, Bertsias G, Lagoudaki E, Bertsias G. Palmoplantar Pustulosis-like Eruption Induced by Baricitinib for Treatment of Rheumatoid Arthritis. EJCRIM 2019;7 doi:10.12890/2019_001383.

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