Isolated Non-Resolving Vulvar Lesion as a Presentation of Disseminated Histoplasmosis in a Woman with HIV

  • Moni Roy Department of Internal Medicine, University of Illinois College of Medicine, OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Ashish Kumar Roy Department of Internal Medicine, University of Illinois College of Medicine, OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Jan Nalinee Upalakalin Department of Pathology, OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Sharjeel Ahmad Department of Internal Medicine, Section of Infectious Diseases, University of Illinois College of Medicine, Peoria, Illinois, USA
DOI: https://doi.org/10.12890/2020_001814

Keywords

Disseminated histoplasmosis, vulvar lesion, HIV, AIDS

Abstract

Disseminated histoplasmosis is most commonly caused by Histoplasma capsulatum and is a known opportunistic infection in immunocompromised patients. The clinical presentation of histoplasmosis varies from asymptomatic to a progressive disseminated form. Pulmonary and CNS involvement is common in disseminated histoplasmosis. Rarely, disseminated disease can present as vulvar lesion in the absence of pulmonary symptoms, causing a delay in diagnosis. As per our PubMed literature search, there have only been two reported cases where vulvar lesion was the only presenting symptom of disseminated disease. In our patient, a histopathological diagnosis was made with staining showing budding yeast forms of histoplasma.

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    • Published: 2020-07-16

    Issue: Vol 7 No 10 (view)

    Section: Articles

    How to cite:
    1.
    Roy M, Roy AK, Upalakalin JN, Ahmad S. Isolated Non-Resolving Vulvar Lesion as a Presentation of Disseminated Histoplasmosis in a Woman with HIV. EJCRIM 2020;7 doi:10.12890/2020_001814.

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