Is There More to This Case than Mere Pulmonary Alveolar Proteinosis? A Clinical Case Presentation

  • Tal Frenkel-Rutenberg Internal Medicine T, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
  • Amir Dagan Internal Medicine T, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
  • Eyal Lotan Internal Medicine T, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
  • Dor Lotan Internal Medicine "T", Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
  • Gad Segal Internal Medicine "T", Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.

Keywords

Pulmonary alveolar proteinosis, GATA2, miscarriage, myelodysplasia syndrome, surfactant

Abstract

Introduction: Pulmonary alveolar proteinosis (PAP) is a rare disease, associated with excess accumulation of surfactant proteins and lipids in the alveoli.

Clinical presentation: We report the case of a 46-year-old woman with a combined presentation of PAP, myelodysplasia and recurrent miscarriages.

Conclusions: The concomitant presentation of the above might be compatible with a mutation of the haematopoietic transcription factor gene GATA2.

Author Biographies

Gad Segal,
Internal Medicine "T", Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel. Head. Internal medicine T,
Sheba medical center
Tel Hashomer
ISRAEL

References

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  • Published: 2015-06-29

    Issue: Vol 2 No 3 (2015) (view)

    Section: Articles

    How to cite:
    Frenkel-Rutenberg, T., Dagan, A., Lotan, E., Lotan, D., & Segal, G. (2015). Is There More to This Case than Mere Pulmonary Alveolar Proteinosis? A Clinical Case Presentation. European Journal of Case Reports in Internal Medicine, 2(3). https://doi.org/https://doi.org/10.12890/2015_000210