A Case of Hypercalcemia in an Immunocompetent Patient with Disseminated Mycobacterium marinum Infection with a Rain Barrel as the Most Likely Primary Source

  • Wendy Uijtendaal Department of Internal Medicine, Ziekenhuisgroep Twente, Almelo, The Netherlands
  • Rima Yohanna Department of Rheumatology, Ziekenhuisgroep Twente, Almelo, The Netherlands
  • Folkert Visser Department of Internal Medicine, Ziekenhuisgroep Twente, Almelo, The Netherlands
  • Paul Ossenkoppele Department of Dermatology, Ziekenhuisgroep Twente, Almelo, The Netherland
  • Dorine Hess Department of Microbiology, Ziekenhuisgroep Twente, Almelo, The Netherlands
  • Dennis Boumans Department of Rheumatology, Ziekenhuisgroep Twente, Almelo, The Netherlands

Keywords

Mycobacterium marinum, hypercalcemia, immunocompetent, polyarthritis, Polyarteritis nodosa

Abstract

Infection with Mycobacterium marinum is common in fish, and so human infection usually arises from contact with contaminated water or fish. A solitary papulonodular lesion on a finger or hand is the typical presentation. Disseminated infections are rare and mostly seen in immunocompromised patients.

We present a rare case of disseminated M. marinum infection presenting with polyarthritis, tenosynovitis, dactylitis, and (sub)cutaneous and intramuscular lesions in an immunocompetent patient. This case was complicated by hypercalcemia, renal failure and eventually death. A contaminated rain barrel was most likely the primary source of the infection.

VIEW THE ENTIRE ARTICLE

References

  • Aubry A, Mougari F, Reibel F, Cambau E. Mycobacterium marinum. Microbiol Spectr 2017;5(2).
  • Johnson MG, Stout JE. Twenty-eight cases of Mycobacterium marinum infection: retrospective case series and literature review. Infection 2015;43(6):655–662.
  • Holden IK, Kehrer M, Andersen AB, Wejse C, Svensson E, Johansen IS. Mycobacterium marinum infections in Denmark from 2004 to 2017: a retrospective study of incidence, patient characteristics, treatment regimens and outcome. Sci Rep 2018;8(1).
  • Nielsen CT, Andersen ÅB. Hypercalcemia and renal failure in a case of disseminated Mycobacterium marinum infection. Eur J Intern Med 2009;20(2):e29–31.
  • Abdulfattah O, Rahman EU, Shweta F, Datar P, Alnafoosi Z, Trauber D, et al. Severe hypercalcemia in a patient with extrapulmonary Mycobacterium abscessus: granuloma or immune reconstitution inflammatory syndrome? First case of Mycobacterium abscessus presenting as retroperitoneal lymphadenopathy with severe hypercalcemia: a case report and literature review. J Community Hosp Intern Med Perspect 2018;8(6):331–338.
  • Published: 2021-11-18

    Issue: 2021: LATEST ONLINE (view)

    Section: Articles

    How to cite:
    1.
    Uijtendaal W, Yohanna R, Visser F, Ossenkoppele P, Hess D, Boumans D. A Case of Hypercalcemia in an Immunocompetent Patient with Disseminated Mycobacterium marinum Infection with a Rain Barrel as the Most Likely Primary Source. EJCRIM 2021;2 doi:10.12890/2021_002864.