Isolated Aortitis Presenting with an Annoying Persistent Cough: A Case Report
  • Michele Maria Luchetti
    Clinica Medica, Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona
  • William Capeci
    Clinica Medica, Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona
  • Matteo Rossini
    Clinica Medica, Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona
  • Devis Benfaremo
    Clinica Medica, Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona
  • Armando Gabrielli
    Clinica Medica, Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona

Keywords

Aortitis, chronic cough, rare diseases

Abstract

Objectives: To report a case of idiopathic aortitis presenting with chronic cough.

Materials and Methods: the Authors describe the case of a 72-year-old man with dry cough, worsening fatigue, weight loss and elevated systemic inflammatory markers.

Results: A PET-CT scan showed diffuse thickening of the thoracic aorta and confirmed the diagnosis of aortitis. Systemic corticosteroid therapy was initiated and complete remission was achieved in six months.

Conclusion: Persistent dry cough of unknown origin, especially when associated with systemic inflammation, demands a thorough differential diagnosis and should not be underrated.

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References

  • Gornik HL, Creager MA. Aortitis. Circulation 2008;117:3039–51.
  • Rojo-Leyva F, Ratliff NB, Cosgrove DM 3rd, Hoffman GS. Study of 52 patients with idiopathic aortitis from a cohort of 1,204 surgical cases. Arthritis Rheum 2000;43:901–907.
  • Van der Schueren B, Lambert M. Cough as the presenting symptom of large vessel vasculitis. Clin Rheumatol 2005;24:411–4.
  • Simpson CB, Amin MR. Chronic Cough: State-of-the-Art Review. Otolaryngol Head Neck Surg 2006;134:693–700.
  • Muto G, Yamashita H, Takahashi Y, Miyata Y, Morooka M, Minamimoto R et al. Large vessel vasculitis in elderly patients: early diagnosis and steroid-response evaluation with FDG-PET/CT and contrast enhanced CT. Rheumatol Int 2014;34:1545–54.
  • Mukhtyar C, Guillevin L, Cid MC, B Dasgupta, K de Groot, W Gross et al. EULAR recommendations for the management of large vessel vasculitis. Ann Rheum Dis 2009;68:318–323.

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    Published: 2016-02-18
    Issue: Vol. 3 No. 2 (view)

    How to cite:
    1.
    Luchetti MM, Capeci W, Rossini M, Benfaremo D, Gabrielli A. Isolated Aortitis Presenting with an Annoying Persistent Cough: A Case Report. EJCRIM 2016;3 doi:10.12890/2016_000360.