First case of meningoencephalitis and bacteraemia with Flavobacterium lindanitolerans
  • Rebecca Zurbuchen
    Department of Medicine, Thun Hospital, Thun, Switzerland
  • Mirjam de Roche
    Department of Medicine, Thun Hospital, Thun, Switzerland
  • Aikaterini Galimanis
    Department of Medicine, Thun Hospital, Thun, Switzerland
  • Kerstin Narr
    Viollier AG, Allschwil, Switzerland
  • Olivier Dubuis
    Viollier AG, Allschwil, Switzerland
  • Christiane Resch
    Department of Medicine, Thun Hospital, Thun, Switzerland
  • Mairi Ziaka
    Department of Medicine, Thun Hospital, Thun, Switzerland


Flavobacterium lindanitolerans, meningoencephalitis, gram-negative bacteria, cerebral infection, bacterial meningitis, gram-negative meningitis


Purpose: Flavobacterium lindanitolerans is an environmental Gram-negative, non-spore-forming rod which is usually not considered to be a human pathogen. Isolation from human clinical samples has been described only once. We report the first case of meningoencephalitis and bacteraemia with Flavobacterium lindanitolerans.
Case description: A 76-year-old female presented with fever, headache, alteration of mental status, marked meningism and dysarthria. A lumbar puncture demonstrated cerebrospinal fluid findings consistent with bacterial meningitis, and a broad-spectrum antibiotic therapy was initiated. Blood and cerebrospinal fluid cultures revealed a growth of Flavobacterium lindanitolerans. Based on antimicrobial susceptibilities testing, antibiotic treatment was changed to levofloxacin, resulting in a remission of the clinical symptoms after 21 days of treatment.
Conclusion: Flavobacterium species are extremely rare human pathogens. However, some of them have been reported to cause opportunistic infections. We describe the first case of meningoencephalitis and bacteraemia caused by Flavobacterium lindanitolerans which was effectively treated with levofloxacin for 21 days.



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    Published: 2023-07-13
    Issue: 2023: Vol 10 No 8 (view)

    How to cite:
    Zurbuchen R, de Roche M, Galimanis A, Narr K, Dubuis O, Resch C, Ziaka M. First case of meningoencephalitis and bacteraemia with Flavobacterium lindanitolerans. EJCRIM 2023;10 doi:10.12890/2023_003980.