Ventricular Fibrillation in Patient with Multi-vessel Coronary Spasm Four Days after the Initiation of Oral Beta-blocker

  • Manabu Kurabayashi Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Hidetoshi Suzuki Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Tsukasa Shimura Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Yasuteru Yamauchi Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City
  • Kaoru Okishige Division of Cardiology, Yokohama City Minato Red Cross Hospital, Yokohama City

Keywords

Coronary spasm, ventricular fibrillation, beta-blocker, acetylcholine provocation test.

Abstract

We describe a case of ventricular fibrillation occurring in a patient with multi-vessel coronary spasm after the initiation of an oral beta-blocker. A 56-year-old man began to experience chest discomfort and his computed tomography revealed intermediate coronary stenoses. He was administered medications including an oral beta-blocker but suddenly collapsed while walking 4 days later. An automated external defibrillator detected ventricular fibrillation and delivered successful electrical cardioversion. An acetylcholine provocation test after stabilization of the status revealed triple-vessel coronary spasm. Beta-blockers may provoke exacerbation of coronary spasm and result in lethal arrhythmia.

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  • Published: 2016-07-27

    Issue: Vol 3 No 5 (view)

    Section: Articles

    How to cite:
    Kurabayashi, M., Suzuki, H., Shimura, T., Yamauchi, Y., & Okishige, K. (2016). Ventricular Fibrillation in Patient with Multi-vessel Coronary Spasm Four Days after the Initiation of Oral Beta-blocker. European Journal of Case Reports in Internal Medicine, 3(5). https://doi.org/https://doi.org/10.12890/2016_000439