Silent Adrenal Pheochromocytoma Coexistent with Corticomedullary Hyperplasia: A Case Incidentally Discovered

  • Luigi Petramala Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Federica Olmati Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Antonio Concistrè Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Vincenza Saraceno Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Gino Iannucci Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome
  • Antonio Ciardi Department of Surgery “Pietro Valdoni”, University “Sapienza”, Rome
  • Giorgio De Toma Department of Surgery “Pietro Valdoni”, University “Sapienza”, Rome
  • Claudio Letizia Specialized Center of Secondary Hypertension, Department of Internal Medicine and Medical Specialties, University “Sapienza”, Rome http://orcid.org/0000-0003-4397-0624

Keywords

Adrenal Incidentaloma, Subclinical Hypercortisolism, Pheochromocytoma, adrenal hyperplasia

Abstract

Introduction: Pheochromocytoma (PHEO) is a rare catecholamine-producing tumour arising from chromaffin cells in the sympatho-adrenal system, and can present as asymptomatic adrenal incidentaloma (AI).

Patient: We describe the case of a 61-year-old woman with a right adrenal mass incidentally discovered, who was biochemically characterized with subclinical hypercortisolism (SH). The patient was scheduled for adrenalectomy because of increasing seizure of the right adrenal gland with a haemorrhagic and focal pseudocystic appearance macroscopically, incidental histological and immunohistochemical PHEO, and micronodular cortico-adrenal hyperplasia.

Discussion: This report describes a rare case of incidental non-functioning PHEO coexisting with corticomedullary hyperplasia and SH.

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  • Published: 2017-10-06

    Issue: Vol 4 No 10 (view)

    Section: Articles

    How to cite:
    Petramala, L., Olmati, F., Concistrè, A., Saraceno, V., Iannucci, G., Ciardi, A., De Toma, G., & Letizia, C. (2017). Silent Adrenal Pheochromocytoma Coexistent with Corticomedullary Hyperplasia: A Case Incidentally Discovered. European Journal of Case Reports in Internal Medicine, 4(10). https://doi.org/https://doi.org/10.12890/2017_000714