Electrolyte Disorders as Triggers for Takotsubo Cardiomyopathy

  • Fabio Andreozzi Department of Internal Medicine, Université Libre de Bruxelles (ULB), Brussels, Belgium
  • Giovanni Cuminetti C.H.U. Brugmann Bruxelles, Belgium
  • Rafik Karmali Internal Medicine Department, Brugmann University Hospital, Brussels, Belgium
  • Prochore Kamgang Internal Medicine Department, Brugmann University Hospital, Brussels, Belgium


Takotsubo cardiomyopathy, hypomagnesemia, hypocalcaemia, heart failure


A 56-year-old woman presented with cognitive impairment, confusion and slowed speech, muscle cramps and peripheral paraesthesia preceded by vomiting. Blood tests revealed severe hypokalaemia, hyponatremia, hypomagnesemia and hypocalcaemia. Following a diagnosis of Takotsubo cardiomyopathy based on ultrasonography, the patient was treated with electrolyte supplementation and recovered within 48h. When heart failure is suspected, electrolyte abnormalities should be carefully ruled out as they can affect cardiac function.



  • De Luca L, Klein L, Udelson JE, Orlandi C, Sardella G, Fedele F, et al. Hyponatremia in patients with heart failure. Am J Cardiol 2005;96:19L–23L.

  • Macdonald JE, Struthers AD. What is the optimal serum potassium level in cardiovascular patients? J Am Coll Cardiol 2004;43:155–161.

  • Solzbach U, Kitterer HR, Haas H. Reversible congestive heart failure in severe hypocalcemia. Herz 2010;35:507–510.

  • Chakraborti S, Chakraborti T, Mandal M, Mandal A, Das S, Ghosh S. Protective role of magnesium in cardiovascular diseases: a review. Mol Cell Biochem 2002;238:163–179.

  • Kazuo K, Miho F, Toshihiro I, Shinichi H, Tohru M. Takotsubo cardiomyopathy: pathophysiology, diagnosis and treatment. World J Cardiol 2014;6:602–609.
  • Published: 2018-02-12

    Issue: Vol. 5 No. 4 (view)

    Section: Articles

    How to cite:
    Andreozzi F, Cuminetti G, Karmali R, Kamgang P. Electrolyte Disorders as Triggers for Takotsubo Cardiomyopathy. EJCRIM 2018;5 doi:10.12890/2018_000760.

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