Life-Saving Combined Heart–Kidney Transplantation in a Previous Sequential Heart and Kidney Transplant Recipient

  • Meenal Sharma Heart & Lung Transplant Unit, St Vincent’s Hospital Sydney, New South Wales, Australia
  • Chris Anthony Heart & Lung Transplant Unit, St Vincent’s Hospital Sydney, New South Wales, Australia
  • Christopher Hayward Heart & Lung Transplant Unit, St Vincent’s Hospital Sydney, New South Wales, Australia
  • Andrew Jabbour Heart & Lung Transplant Unit, St Vincent’s Hospital Sydney, New South Wales, Australia
  • Anne M Keogh Heart & Lung Transplant Unit, St Vincent’s Hospital Sydney, New South Wales, Australia
  • Peter Macdonald Heart & Lung Transplant Unit, St Vincent’s Hospital Sydney, New South Wales, Australia
  • Jacob Sevastos Department of Nephrology, St Vincent’s Hospital Sydney, New South Wales, Australia
DOI: https://doi.org/10.12890/2018_000924

Keywords

Heart kidney transplantation, combined heart kidney transplantation, recipient of multiple transplanted organs, trasplant

Abstract

Purpose: Solid organ re-transplantation in the context of allograft failure is a challenging clinical and ethical problem. Ideally, solid organ re-transplantation after initial allograft failure should be performed in all recipients, but this is often not clinically or logistically feasible.
Methods: This report details what we believe is the first combined heart–kidney transplant in a recipient of a previous sequential heart and kidney transplant. Results: Eight years after a combined heart and kidney transplant after initially receiving a sequential heart and kidney transplant, a 31-year-old man is doing extremely well, with no rejection episodes or significant complications after transplantation.
Summary: This case confirms that combined heart and kidney transplantation is a viable option for tackling the complex issue of graft failure in recipients of previous cardiac and renal grafts.

VIEW THE ENTIRE ARTICLE

References

  • Alam A, Badovinac K, Ivis F, Trpeski L, Cantarovich M. The outcome of heart transplant recipients following the development of end-stage renal disease: analysis of the Canadian Organ Replacement Register (CORR). Am J Transplant 2007;7:461–465.

  • Cassuto JR, Reese PP, Sonnad S, et al. Wait list death and survival benefit of kidney transplantation among nonrenal transplant recipients. Am J Transplant 2010;10:2502–2511.

  • Gill J, Shah T, Hristea I, et al. Outcomes of simultaneous heart–kidney transplant in the US: a retrospective analysis using OPTN/UNOS data. Am J Transplant 2009;9:844–852.

  • Russo MJ, Rana A, Chen JM, et al. Pretransplantation patient characteristics and survival following combined heart and kidney transplantation: an analysis of the United Network for Organ Sharing Database. Arch Surg 2009;144:241–246.

  • Lindenfield, J, Miller GG, Shakar SF, Zolty R, et al. Drug therapy in the heart transplant recipient part 1: cardiac rejection and immunosuppressive drugs. Circulation 2004;110:3734–3740.

    • Published: 2018-06-19

    Issue: Vol 5 No 8 (view)

    Section: Articles

    How to cite:
    1.
    Sharma M, Anthony C, Hayward C, Jabbour A, Keogh AM, Macdonald P, Sevastos J. Life-Saving Combined Heart–Kidney Transplantation in a Previous Sequential Heart and Kidney Transplant Recipient. EJCRIM 2018;5 doi:10.12890/2018_000924.