European Journal of Case Reports in Internal Medicine


The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM). The journal wants to promote the practice of internal medicine in Europe. Its aim is to provide a forum to internal medicine doctors.
EJCRIM welcomes papers describing unusual or complex cases and case series that an internist may encounter in everyday practice. Case series are also welcomed as long as they demonstrate the appropiateness of a therapeutical approach or unusual manifestation of a disease.
The journal would also consider brief reasoned reports of issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to scientific meetings of European societies of Internal Medicine.

EJCRIM is peer-reviewed with single-blind review and freely accessible to all.

Yanet Parodis Lopez, Nery Sablon Gonzalez, Noel Lorenzo Villalba, Rafael Camacho Galvan, Jose Carlos Rodriguez Perez
Ahmed Gabr, Khalid El Kholy, James Crotty, Margaret O’Connor, Elijah Chaila
Manabu Kurabayashi, Hidetoshi Suzuki, Tsukasa Shimura, Yasuteru Yamauchi, Kaoru Okishige
Eleni Mylona, Styliani Golfinopoulou, Pelagia Sfakianaki, George Kyriakopoulos, Ioannis Tsonis, Theofanis Apostolou, Christina Vourlakou, Athanasios Skoutelis
Elena A. Kochmareva, Valentin A. Kokorin, Evgenia A. Kondrashova, Nadejda V. Khokhlova, Argishti G. Vardanyan, Ilya A. Kokorin, Dmitry A. Doroshenko
Michele Mondoni, Paolo Carlucci, Elena Maria Parazzini, Paolo Busatto, Stefano Centanni
Kristien Velding, Bert Mulder, Jeroen Oeben, Annelies Suurmeijer, Thiemo F Veneman
Senthil Chandrasekaram, Ranga H Fernando, Vikram Aaarella, Emily T Mudenha, Devaka J Fernando

A Rare Presentation of Leptospirosis

Filipa Silva, Mariana Brandão, Afonso Esteves
Published: 26/08/2016


Leptospirosis has a wide spectrum of clinical manifestations. Acute renal failure, an important complication, generally involves interstitial and tubular damage. We describe the case of a 42-year-old man who was admitted with fever, back pain and periorbital oedema. He had hypertension, thrombocytopenia, acute renal failure, hypoalbuminaemia, hypertriglyceridaemia and proteinuria >4.00 g/l. The renal biopsy showed mesangioproliferative glomerulonephritis. Due to the epidemiological context and clinical picture, ceftriaxone was started with rapid clinical improvement. Blood PCR for leptospira came back positive. The presentation of leptospirosis as nephrotic syndrome is rare and this diagnosis should be considered before performing a renal biopsy.