A hepatic manifestation of anorexia nervosa
  • Jodi-Anne M. Wallace
    Department of Internal Medicine, Division of Hospital Medicine, University of Florida, Gainesville, Florida, USA https://orcid.org/0000-0001-7590-2971
  • Krizia-Ivana T. Udquim
    Department of Internal Medicine, Division of Hospital Medicine, University of Florida, Gainesville, Florida, USA
  • Thomas A. Starnes
    Asheville Orthopaedic Associates, Asheville, North Carolina, USA
  • Nila S. Radhakrishnan
    Department of Internal Medicine, Division of Hospital Medicine, University of Florida, Gainesville, Florida, USA https://orcid.org/0000-0002-7666-356X

Keywords

Anorexia nervosa, hepatitis, acute liver injury

Abstract

A 30-year-old woman with a history of anorexia nervosa was admitted with weight loss, hypoglycaemia and electrolyte disturbances. During her admission, transaminases peaked at ALP 457 U/l, AST 817 U/l and ALT 1066 U/l. Imaging and laboratory findings were unrevealing, and she declined liver biopsy. Nutrition was introduced via a nasogastric tube and she demonstrated improvement in her laboratory values over several weeks. Her transaminitis was determined to be secondary to severe malnutrition, which has been previously described, but cases with such profound transaminitis are less common. Studies have demonstrated hepatic autophagocytosis as the likely cause.

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    Published: 2023-04-27
    Issue: 2023: Vol 10 No 5 (view)

    How to cite:
    1.
    Wallace J-AM, Udquim K-IT, Starnes TA, Radhakrishnan NS. A hepatic manifestation of anorexia nervosa. EJCRIM 2023;10 doi:10.12890/2023_003675.