Inverted Variant of Takotsubo Syndrome Caused by Inhaled Adrenergic Beta-2 Agonists

Authors

• Marta de Sousa Internal Medicine Department, Centro Hospitalar do Médio Tejo, E.P.E., Torres Novas, Portugal
• André Casado Intensive Care Unit, Hospital da Luz, Lisbon, Portugal
• Alexandre Buinhas Marques Intensive Care Unit, Hospital da Luz, Lisbon, Portugal
• Francisco Pereira Machado Cardiology Department, Hospital da Luz, Lisbon, Portugal
• Isabel Esperança Intensive Care Unit, Hospital da Luz, Lisbon, Portugal

diorke@hotmail.com

Keywords

Abstract

Takotsubo syndrome (TS) is an acute and reversible clinical syndrome characterized by transient hypokinesis of the left ventricular (LV) apex. Variant forms of LV dysfunction have been reported, including inverted Takotsubo syndrome (ITS), which represents only 5% of cases and has previously been linked to excessive use of inhaled adrenergic beta-2 agonists. The authors describe the case of a 60-year-old female patient who was diagnosed with ITS after the excessive use of inhaled adrenergic beta-2 agonists. This case highlights an uncommon variant of this syndrome that may not be obvious and must be suspected in this particular context.