A simple score (BECLAP Score) is accurate in predicting early mortality in frail medical non-oncologic patients, and may help physicians to identify management priorities.
Prognosis has a central role in clinical decision-making, but most studies address medium-long term prognosis, e.g. mortality at 1 year. Still what is crucial in clinical decisions is short-term prognosis, i.e. 3-months mortality, that was not addressed previously as primary outcome in prognostic studies. Indeed, life expectancy of three months is now deemed a condition in which palliative care should be considered, activating appropriate protocols.
In a prospective observational study (Brucato et al. Eur J Int Med 2019 [Epub ahead of print]) 2788 consecutive patients admitted in 5 Italian Internal Medicine units were prospectively screened; 644 oncologic patients were excluded; 2144 non-oncologic patients (1021 female) were followed-up for mortality for 6 months. Main outcome was 3-months mortality in permanently bedridden inpatients with at least 2 of: creatinine clearance <35 ml/min; albumin <2.5 mg/dl; at least 2 hospital admissions in the previous 6 months. Advanced dementia and dysphagia were also recorded.
Approximately two out of three non-oncologic medical patients permanently bedridden having 2 of the abovementioned items were dead 3 months after index admission.
A simple score was calculated in a training cohort and validated in validation cohort. The BECLAP-D score is a validated score that includes just 6 very SIMPLE items:
- AGE
- SEX
- TO BE OR NOT PERMANENTLY BEDRIDDEN
- the value of calculated CREATININE CLEARANCE
- The ALBUMIN value
- presence or absence of clinically relevant DYSPHAGIA
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This score accurately predicts the probability of mortality at 3 months in frail non-oncologic patients permanently bedridden, and may be very useful in discussing management priorities.