Hypercalcemia and Extensive Chest Metastasis of Vulvar Squamous Cell Carcinoma

  • Ernestina Natália Mota Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Isabel Paulos Mesquita Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Carlos Pires Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Rui M.M. Victorino Serviço de Medicina, Hospital Santa Maria, Faculdade de Medicina de Lisboa, Centro Hospitalar Lisbona Norte, Lisbon, Portugal
DOI: https://doi.org/10.12890/2019_001218

Keywords

Squamous cell carcinoma of the vulva, paraneoplastic hypercalcemia, pulmonary metastasis of vulvar squamous cell carcinoma

Abstract

A 73-year-old woman with a diagnosis of vulvar carcinoma submitted to curative surgery 5 years previously, presented to the emergency department with prostration and vulvar haemorrhage. Although the gynaecological examination was unremarkable, she had a mass in the left chest wall and hypercalcemia. A CT scan of the thorax revealed a voluminous left hemithorax mass invading the mediastinum, lung, pleura and chest wall. Ultrasound-guided biopsy of the mass showed infiltration by a well-differentiated keratinizing squamous cell carcinoma (SCC). This case report describes an extremely rare metastatic pattern in vulvar SCC concomitant with paraneoplastic hypercalcemia.

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    • Published: 2019-09-02

    Issue: Vol 6 No 9 (view)

    Section: Articles

    How to cite:
    1.
    Mota EN, Mesquita IP, Pires C, Victorino RM. Hypercalcemia and Extensive Chest Metastasis of Vulvar Squamous Cell Carcinoma. EJCRIM 2019;6 doi:10.12890/2019_001218.