Multi-Focal Splenic Tumour in a Belgian Patient and a Brief Review of the Literature on Littoral Cell Angioma
  • Maaike Ramael
    Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
  • Patrick Schoeters
    Department of Gastro-enterology, General Hospital AZ Herentals, Herentals, Belgium
  • Karl De Pooter
    Department of Abdominal Surgery, General Hospital AZ Herentals, Herentals, Belgium
  • Frederik Van Sonhoven
    Department of Medical and Molecular Imaging, General Hospital AZ Herentals, Herentals, Belgium
  • Hilde Van Steelandt
    Department of Medical and Molecular Imaging, General Hospital AZ Herentals, Herentals, Belgium
  • Jacqueline Swaegers
    Department of Radiology, Hôpital du Valais, Sion, Switzerland
  • Wim Develter
    Department of Pathology and Molecular Pathology, Heilig Hartziekenhuis Lier, Lier, Belgium
  • Marc Ramael
    Department of Pathology and Molecular Pathology, Heilig Hartziekenhuis Lier, Lier, Belgium; Laboratory of Histology and Cell Biology, University of Antwerp, Antwerp, Belgium

Keywords

Littoral cell tumour, spleen, CT scan, immunohistochemistry

Abstract

We describe the case of a 66-year-old woman with littoral cell angioma (LCA) confirmed by histopathology and immunohistochemistry, to our knowledge the first case in Belgium. LCA is an extremely rare primary vascular tumour of the splenic red pulp, probably originating from littoral cells. If a splenic mass and nodules are incidentally identified on imaging and the patient has no associated signs or symptoms, LCA should be suspected. Histopathology and adjacent techniques are mandatory for definitive diagnosis. Splenectomy followed by adequate follow-up is necessary to exclude underlying pathology.

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References

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  • Liu Z, Zhu J, Peng L, Tu Y, Li Y, Xiao W. Littoral cell angioma of the spleen: three cases report and literature review. Int J Clin Exp Med 2018;11(2):1077–1081.
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    Published: 2020-08-29
    Issue: 2020: Vol 7 No 11 (view)

    How to cite:
    1.
    Ramael M, Schoeters P, De Pooter K, Van Sonhoven F, Van Steelandt H, Swaegers J, Develter W, Ramael M. Multi-Focal Splenic Tumour in a Belgian Patient and a Brief Review of the Literature on Littoral Cell Angioma . EJCRIM 2020;7 doi:10.12890/2020_001863.

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