Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
  • Kadhim Al-banaa
    Department of Haemostasis and Thrombosis, University of California San Diego Health, San Diego, CA, USA
  • Alfarooq Alshaikhli
    Department of Medicine, University of Texas/Rio Grande Valley, Edinburg, TX, USA
  • Asal AL-Hareeri
    Department of Surgery, Harborview Medical Center, Seattle, WA, USA
  • Mohammed Abdelhalim
    Department of Medicine, Beaumont Hospital, Dearborn, MI, USA
  • Alsadiq Al-Hillan
    Department of Gastroenterology, Beaumont Hospital, Royal Oak, MI, USA
  • Tejas Joshi
    Department Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA


Antiphospholipid antibody syndrome, APS, arterial dissection, vasculopathy, stroke mimic


Antiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe two patients with APS who developed ischaemic stroke as a result of vertebral artery dissection in the absence of acquired and genetic risk factors for arterial dissection. We also conducted a systematic review of the literature for cases of arterial dissection associated with APS. We suspect that APS may be a potential cause of vasculopathy and arterial dissection. Further research is needed to explore this possible association.



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    Published: 2021-05-24
    Issue: 2021: Vol 8 No 5 (view)

    How to cite:
    Al-banaa K, Alshaikhli A, AL-Hareeri A, Abdelhalim M, Al-Hillan A, Joshi T. Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review. EJCRIM 2021;8 doi:10.12890/2021_002610.