Sirolimus-Induced Rash in a Kidney Transplant Patient
  • Zachary Bruss
    Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA
  • Shanza Farook
    Department of Internal Medicine, Shifa International Hospital, Islamabad, Pakistan
  • Sana Shah
    Aga Khan University, Karachi, Pakistan
  • Abu Baker Sheikh
    Department of Internal Medicine, Division of Hospital Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA


Maculopapular rash, renal transplant


Sirolimus is an inhibitor of the mammalian target of rapamycin, which is used in kidney transplant immunosuppression. The clinical spectrum of cutaneous adverse events associated with sirolimus use varies, with maculopapular rash being an uncommon side effect very rarely reported in the literature. We present the case of a 78-year-old male renal transplant recipient who developed a diffuse maculopapular pruritic rash after starting sirolimus. This case report demonstrates that maculopapular rash is an uncommon sirolimus-related side effect that must be identified promptly so the medication can be discontinued and rash progression prevented.



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    Published: 2022-09-22
    Issue: 2022: Vol 9 No 9 (view)

    How to cite:
    Bruss Z, Farook S, Shah S, Baker Sheikh A. Sirolimus-Induced Rash in a Kidney Transplant Patient. EJCRIM 2022;9 doi:10.12890/2022_003565.