A rare convergence: adult-onset Langerhans cell histiocytosis and HIV infection
  • Andronikos Spyrou
    First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Michalis Ploumidis
    First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Sofia Nanousi
    First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Charis Roumbas
    Pathology Department, General Hospital of Athens ‘G. Gennimatas’, Athens, Greece
  • Georgios Adamis
    First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece
  • Myrto Astriti
    First Department of Internal Medicine-Infectious Diseases Unit, General Hospital of Athens 'G. Gennimatas', Athens, Greece

Keywords

Langerhans cell histiocytosis, adult-onset, HIV

Abstract

While primarily described in children, adult-onset Langerhans cell histiocytosis (LCH) has been reported, albeit infrequently. In the present scenario, we unveil a unique case of adult-onset LCH in an HIV-infected individual. After the diagnosis was made, the patient was successfully treated and demonstrated total disease remission. This case illustrates the diagnostic challenge that rare clinical entities such as LCH pose, especially in the context of an untreated HIV infection. Furthermore, the complexity of treating adult-onset Langerhans cell histiocytosis in an HIV-positive patient is highlighted, with emphasis given on a multidisciplinary approach.

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    Published: 2023-11-24
    Issue: 2023: Vol 10 No 12 (view)

    How to cite:
    1.
    Spyrou A, Ploumidis M, Nanousi S, Roumbas C, Adamis G, Astriti M. A rare convergence: adult-onset Langerhans cell histiocytosis and HIV infection. EJCRIM 2023;10 doi:10.12890/2023_004168.