Successful chemotherapy treatment for a tricuspid valvular stenosis patient due to right ventricular lymphoma
  • Do Van Chien
    Department of Cardiovascular Intensive Care Unit, 108 Central Military Hospital, Hanoi, Vietnam
  • Tran Quoc Quy
    Department of Cardiovascular Intensive Care Unit, 108 Central Military Hospital, Hanoi, Vietnam


Tricuspid valvular stenosis, right ventricular lymphoma, chemotherapy


Background: This study presents a patient diagnosed with tricuspid valvular stenosis due to right ventricular lymphoma, who was treated successfully.
Case presentation: A 66-year-old man with a history of worsening shortness of breath during activity for the last three weeks sought medical attention. The patient later experienced swelling in the extremities, fluid build-up around the lungs and abdominal fluid accumulation, with no reported chest pain, fever, or weight loss. An echocardiogram found a mass in the lateral wall near the tricuspid valve of the right ventricle, leading to moderate tricuspid stenosis. The cardiac magnetic resonance imaging (MRI) revealed a lumpy, poorly defined mass that invaded the heart muscle and displayed varied enhancement after contrast administration. Suspicion arose for a malignant tumour or metastatic lesion due to its features and contrast uptake capability. A percutaneous biopsy was carried out on the mass in the right ventricle to confirm the diagnosis. The pathology report indicated a diagnosis of non-Hodgkin’s lymphoma. After being diagnosed, the patient underwent chemotherapy using the R-CHOP regimen. Over time the symptoms improved, and echocardiograms revealed a decrease in the size of the tumour. After undergoing six rounds of chemotherapy, a cardiac MRI four months later showed no signs of a tumour. After that, the patient resumed their regular activities.
Conclusion: Right ventricular tumours are mostly malignant lesions and often have an inferior prognosis. Early diagnosis with imaging techniques and myocardial biopsy is necessary to deliver life-saving treatment quickly.



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    Published: 2024-03-25
    Issue: 2024: Vol 11 No 4 (view)

    How to cite:
    Chien DV, Quy TQ. Successful chemotherapy treatment for a tricuspid valvular stenosis patient due to right ventricular lymphoma. EJCRIM 2024;11 doi:10.12890/2024_004451.