Successful chemotherapy treatment for a tricuspid valvular stenosis patient due to right ventricular lymphoma
  • Do Van Chien
    Department of Cardiovascular Intensive Care Unit, 108 Central Military Hospital, Hanoi, Vietnam
  • Tran Quoc Quy
    Department of Cardiovascular Intensive Care Unit, 108 Central Military Hospital, Hanoi, Vietnam

Keywords

Tricuspid valvular stenosis, right ventricular lymphoma, chemotherapy

Abstract

Background: This study presents a patient diagnosed with tricuspid valvular stenosis due to right ventricular lymphoma, who was treated successfully.
Case presentation: A 66-year-old man with a history of worsening shortness of breath during activity for the last three weeks sought medical attention. The patient later experienced swelling in the extremities, fluid build-up around the lungs and abdominal fluid accumulation, with no reported chest pain, fever, or weight loss. An echocardiogram found a mass in the lateral wall near the tricuspid valve of the right ventricle, leading to moderate tricuspid stenosis. The cardiac magnetic resonance imaging (MRI) revealed a lumpy, poorly defined mass that invaded the heart muscle and displayed varied enhancement after contrast administration. Suspicion arose for a malignant tumour or metastatic lesion due to its features and contrast uptake capability. A percutaneous biopsy was carried out on the mass in the right ventricle to confirm the diagnosis. The pathology report indicated a diagnosis of non-Hodgkin’s lymphoma. After being diagnosed, the patient underwent chemotherapy using the R-CHOP regimen. Over time the symptoms improved, and echocardiograms revealed a decrease in the size of the tumour. After undergoing six rounds of chemotherapy, a cardiac MRI four months later showed no signs of a tumour. After that, the patient resumed their regular activities.
Conclusion: Right ventricular tumours are mostly malignant lesions and often have an inferior prognosis. Early diagnosis with imaging techniques and myocardial biopsy is necessary to deliver life-saving treatment quickly.

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References

  • Nomoto N, Tani T, Konda T, Kim K, Kitai T, Ota M, et al. Primary and metastatic cardiac tumors: echocardiographic diagnosis, treatment and prognosis in a 15-years single center study. J Cardiothorac Surg 2017;12:103.
  • Paraskevaidis IA, Michalakeas CA, Papadopoulos CH, Anastasiou-Nana M. Cardiac tumors. ISRN Oncol 2011;2011:208929.
  • Pradella S, Grazzini G, Letteriello M, De Amicis C, Grassi R, Maggialetti N, et al. Masses in right side of the heart: spectrum of imaging findings. Acta Biomed 2020;91:60–70.
  • Zaharia L, Gill PS. Primary cardiac lymphoma. Am J Clin Oncol 1991;14:142–145.
  • Chen K-W, Chang J-H, Yeh S-P, Lu C-R. Primary cardiac B-cell lymphoma with atrioventricular block and paroxysmal ventricular tachycardia. J Cardiothorac Surg 2012;7:70.
  • Miguel CE, Bestetti RB. Primary cardiac lymphoma. Int J Cardiol 2011;149:358–363.
  • Antoniades L, Eftychiou C, Petrou PM, Bagatzounis A, Minas M. Primary cardiac lymphoma: case report and brief review of the literature. Echocardiography 2009;26:214–219.
  • Montiel V, Maziers N, Dereme T. Primary cardiac lymphoma and complete atrio-ventricular block: case report and review of the literature. Acta Cardiol 2007;62:55–58.
  • Jonavicius K, Salcius K, Meskauskas R, Valeviciene N, Tarutis V, Sirvydis V. Primary cardiac lymphoma: two cases and a review of literature. J Cardiothorac Surg 2015;10:138.
  • Petrich A, Cho SI, Billett H. Primary cardiac lymphoma: an analysis of presentation, treatment, and outcome patterns. Cancer 2011;117:581–589.
  • Chin JY, Chung MH, Kim JJ, Lee JH, Kim JH, Maeng IH, et al. Extensive primary cardiac lymphoma diagnosed by percutaneous endomyocardial biopsy. J Cardiovasc Ultrasound 2009;17:141–144.
  • Mohri T, Igawa O, Isogaya K, Hoshida K, Togashi I, Soejima K. Primary cardiac B-cell lymphoma involving sinus node, presenting as sick sinus syndrome. HeartRhythm Case Rep 2020;6:694–696.
  • Jung YH, Woo IS, Ko YJ, Lee JH, Lim JW, Han CW. A case of primary cardiac lymphoma showing isolated central nervous system relapse. Clin Lymphoma Myeloma Leuk 2014;14:e31–33.
  • Chalabreysse L, Berger F, Loire R, Devouassoux G, Cordier J-F, Thivolet-Bejui F. Primary cardiac lymphoma in immunocompetent patients: a report of three cases and review of the literature. Virchows Arch 2002;441:456–461.
  • Burling F, Devlin G, Heald S. Primary cardiac lymphoma diagnosed with transesophageal echocardiography-guided endomyocardial biopsy. Circulation 2000;101:e179–e181.
  • Utsunomiya D, Awai K, Urata J, Hirayama T, Yamashita Y. Primary cardiac lymphoma: computed tomography and magnetic resonance imaging features. Jpn J Radiol 2009;27:243–246.
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    Published: 2024-03-25
    Issue: 2024: Vol 11 No 4 (view)


    How to cite:
    1.
    Chien DV, Quy TQ. Successful chemotherapy treatment for a tricuspid valvular stenosis patient due to right ventricular lymphoma. EJCRIM 2024;11 doi:10.12890/2024_004451.