Fundic Gland Polyposis Associated with Proton-Pump Inhibitor Use
  • Kenta Hamada
    Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka http://orcid.org/0000-0003-0768-3783
  • Yoji Takeuchi
    Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka
  • Tomofumi Akasaka
    Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka
  • Hiroyasu Iishi
    Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka

Keywords

Fundic gland polyp, gastric polyp, proton-pump inhibitor

Abstract

We describe the case of a man with fundic gland polyposis associated with proton-pump inhibitor (PPI) use. Some investigators have reported an association between long-term PPI use and an increase in the risk of developing fundic gland polyps (FGPs). These FGPs are considered to be reversible on stopping PPI treatment. The current patient had used a PPI for 10 years, resulting in multiple FGPs in his gastric body. However, 6 months after cessation of the PPI, the FGPs had obvously regressed, even though a histamine-2 receptor antagonist had subsequently been prescribed. This case demonstrates a link between PPI treatment and FGPs.

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    Published: 2017-06-29
    Issue: Vol. 4 No. 5 (view)


    How to cite:
    1.
    Hamada K, Takeuchi Y, Akasaka T, Iishi H. Fundic Gland Polyposis Associated with Proton-Pump Inhibitor Use. EJCRIM 2017;4 doi:10.12890/2017_000607.