Immune Thrombocytopenia Associated with Mycoplasma pneumoniae Infection

  • Catarina Gouveia Hospital Beatriz Ângelo
  • Vasco Evangelista Beatriz Ângelo Hospital, Loures, Portugal
  • Raquel Almeida Beatriz Ângelo Hospital, Loures, Portugal
  • António Martins Baptista Beatriz Ângelo Hospital, Loures, Portugal

Keywords

Immune thrombocytopenia, Mycoplasma pneumoniae, rituximab

Abstract

Immune thrombocytopenia (ITP) related to Mycoplasma pneumoniae infection is a rare condition and usually associated with a severe clinical course. We here report a case of a young man with a clinical diagnosis of severe ITP secondary to M. pneumoniae infection. The clinical features, therapy and outcome are presented.

References

  • Waites KB, Talkington DF. Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbiol Rev 2004;17:697–728.

  • Kottayam R, Rozenberg G, Cohn RJ. Unusual haematologic manifestations of Mycoplasma pneumoniae infection. J Paediatr Child Health 2007;43:80–82.

  • Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med 2002;346:995–1008.

  • Biberfeld G, Norberg R. Circulating immune complexes in Mycoplasma pneumoniae infection. J Immunol 1974;112:413–415.

  • Tsai YM, Lee PP, Liu CH. A case of primary atypical pneumonia complicated with severe thrombocytopenia. Taiwan Yi Xue Hui Za Zhi 1985;84:742–746.

  • Miller SN, Ringler RP, Lipshutz MD. Thrombocytopenia and fatal intracerebral hemorrhage associated with Mycoplasma pneumonia pneumonia. N Y State J Med 1986; 86:605–607.

  • Veenhoven WA, Smithuis RH, Kerst AJ. Thrombocytopenia associated with Mycoplasma pneumoniae infection. Neth J Med 1990; 37:75–76.

  • Beattie RM. Mycoplasma and thrombocytopenia. Arch Dis Child 1993; 68:250.

  • Pugliese A, Levchuck S, Cunha BA. Mycoplasma pneumoniae induced thrombocytopenia. Heart Lung 1993;22:373–375.

  • Isoyama K, Yamada K. Previous Mycoplasma pneumoniae infection causing severe thrombocytopenic purpura. Am J Hematol 1994; 47:252–253.

  • Venkatesan P, Patel V, Collingham KE, Ellis CJ. Fatal thrombocytopenia associated with Mycoplasma pneumoniae infection. J Infect 1996; 33:115–117.

  • Scimeca PG, James-Herry AG. Severe, acute thrombocytopenia complicating Mycoplasma infection. Pediatr Hematol Oncol 1994;11:557–559.

  • Okoli K, Gupta A, Irani F, Kasmani R. Immune thrombocytopenia associated with Mycoplasma pneumonia infection: a case report and review of literature. Blood Coagul Fibrinolysis 2009;20:595-8

  • Aviner S, Miskin H, London D, Horowitz S, Schlesinger M. Mycoplasma pneumonia infection: A possible trigger for immune thrombocytopenia. Indian J Hematol Blood Transfus 2011;27:46-50.
  • Published: 2018-01-22

    Issue: Vol 5 No 3 (view)

    Section: Articles

    How to cite:
    Gouveia, C., Evangelista, V., Almeida, R., & Baptista, A. (2018). Immune Thrombocytopenia Associated with Mycoplasma pneumoniae Infection. European Journal of Case Reports in Internal Medicine, 5(3). https://doi.org/https://doi.org/10.12890/2018_000817