Vogt-Koyanagi-Harada disease, a rare entity in Spain: the challenge of worldwide immigration and globalization
  • Alberto Benavente Fernández
    Internal Medicine Department, Baza Hospital, Granada, Spain
  • Sara Pérez Moyano
    Internal Medicine Department, Baza Hospital, Granada, Spain
  • Husein Husein-ElAhmed
    Dermatology Department, Baza Hospital, Granada, Spain
  • Ana María Alfaro Juárez
    Ophthalmology Department, Baza Hospital, Granada, Spain

Keywords

Vogt–Koyanagi–Harada disease, uveo-meningeal syndromes, aseptic meningitis

Abstract

Vogt–Koyanagi–Harada disease is rare, mediated by autoimmune melanocyte inflammation and facilitated by genetic predisposition[1-3]. The main clinical features include uveitis, meningitis, tinnitus and sensorineural deafness, and skin and hair depigmentation. It usually develops in four consecutive stages: prodromal, acute uveitic, convalescent, and chronic or recurrent[4]. In view of the first two stages, the differential diagnosis takes into account uveo-meningeal syndromes. Treatment is based on high dose corticosteroids. We present the case of a 14-year-old girl admitted to hospital with fever, progressive uveo-meningeal symptoms, and sensorineural hearing loss. After work-up, the final diagnosis of Vogt–Koyanagi–Harada disease was made.

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References

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    Published: 2018-05-08
    Issue: Vol 5 No 7 (view)

    How to cite:
    1.
    Benavente Fernández A, Pérez Moyano S, Husein-ElAhmed H, Alfaro Juárez AM. Vogt-Koyanagi-Harada disease, a rare entity in Spain: the challenge of worldwide immigration and globalization. EJCRIM 2018;5 doi:10.12890/2018_000886.