Ischemic Stroke as the Initial Manifestation of Neurosyphilis in a Young Adult Patient Positive for Human Immunodeficiency Virus
  • Ayaka Numao
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Keisuke Suzuki
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Hidehiro Takekawa
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Toshiki Nakamura
    Department of Neurology, Rehabilitation Amakusa Hospital, Saitama
  • Hisatake Iwanami
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Naoki Izawa
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Akio Iwasaki
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Hiroaki Fujita
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Yuji Watanabe
    Department of Neurology, Dokkyo Medical University, Tochigi
  • Koichi Hirata
    Department of Neurology, Dokkyo Medical University, Tochigi

Abstract

A 31-year-old man with pontine infarction was referred to our hospital for further evaluation and treatment. At admission, his neurological examination was unremarkable. No lymphadenopathy or skin lesions were found. The Treponema pallidum haemagglutination test, rapid plasma regain test and fluorescent treponemal antibody absorption test of immunoglobulin G were positive in both serum and cerebrospinal fluid (CSF). CSF analysis showed lymphocytic pleocytosis. The patient had male-to-male sexual contact and was found to be HIV positive. Physicians should be aware that acute ischaemic stroke may be the first manifestation of neurosyphilis in a young adult, especially with HIV infection.

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    Published: 2014-07-31
    Issue: Vol. 1 (2014) (view)

    How to cite:
    1.
    Numao A, Suzuki K, Takekawa H, Nakamura T, Iwanami H, Izawa N, Iwasaki A, Fujita H, Watanabe Y, Hirata K. Ischemic Stroke as the Initial Manifestation of Neurosyphilis in a Young Adult Patient Positive for Human Immunodeficiency Virus. EJCRIM 2014;1 doi:10.12890/2014_000097.