Non-acute Transient Reversible Adrenal Insufficiency in a Survivor of Critical Illness: A Lesser-known Cause of Primary Adrenal Insufficiency.
  • Senthil Chandrasekeram
    Department of Endocrinology and Diabetes King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton- in – Ashfield
  • Rebecca Parker
    Department of Endocrinology and Diabetes King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton- in – Ashfield
  • Emily Mudenha
    Department of Endocrinology and Diabetes King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton- in – Ashfield
  • Devaka J Fernando
    Sherwood Forest Hospitals Foundation NHS Trust, University of Sheffield, Sheffield Hallam University

Abstract

Objectives: Primary adrenal insufficiency AI is regarded as a progressive disease needing lifelong replacement therapy, but this may not always be the case.

Material and methods: A non-acute presentation of AI following a hypotensive episode caused by blood loss was investigated.

Results: Adrenal function fully recovered without treatment.

Conclusions: There should be a high index of suspicion and a low threshold for performing tests of adrenal function in survivors of critical illness and severe hypotensive episodes.

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References

  • Arlt W, Allolio B. Adrenal insufficiency. Lancet 2003;361:1881–1893.
  • Smans LC, Zelissen PM. Partial recovery of adrenal function in a patient with autoimmune Addison’s disease. J Endocrinol Invest 2008;31:672–674.
  • Merry WH, Caplan RH, Wickus GG, Reynertson RH, Kisken WA, Cogbill TH, et al. Postoperative acute adrenal failure caused by transient corticotropin deficiency. Surgery 1994;116:1095–1100.
  • Xarli VP, Steele AA, Davis PJ, Buescher ES, Rios CN, Garcia-Bunuel R. Adrenal hemorrhage in the adult. Medicine (Baltimore) 1978;57:211–221.
  • Hekimian G, Baugnon T, Thuong M, Monchi M, Dabbane H, Jaby D, et al. Cortisol levels and adrenal reserve after successful cardiac arrest resuscitation. Shock 2004;22:116—119
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    Published: 2014-07-28
    Issue: Vol. 1 (2014) (view)


    How to cite:
    1.
    Chandrasekeram S, Parker R, Mudenha E, Fernando DJ. Non-acute Transient Reversible Adrenal Insufficiency in a Survivor of Critical Illness: A Lesser-known Cause of Primary Adrenal Insufficiency. EJCRIM 2014;1 doi:10.12890/2014_000098.