Mandibular Osteonecrosis Associated with Antacid Therapy (Esomeprazole)

  • Simone Marconcini Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Enrica Giammarinaro Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Saverio Cosola Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Anna Maria Genovesi Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Ugo Covani Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy

Keywords

Mandibular osteonecrosis, antacid therapy, esomeprazole, osteonecrosis of the jaw, proton pump inhibitors

Abstract

Introduction: Osteonecrosis of the jaw has been consistently reported in the literature associated to the high-dose intravenous bisphosphonate therapy. However, osteonecrosis can also occur in patients who have other risk factors.
Case description: An unusual case of ONJ in a patient being treated with esomeprazole is reported.
Discussion: The probable association between proton pump inhibitor intake and osteonecrosis of the jaw should alert clinicians. Collaborations between medical and dental doctor and an early diagnosis might prevent or reduce the morbidity resulting from advanced destructive lesions of the jaw bone.

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  • Published: 2019-10-14

    Issue: Vol 6 No 10 (view)

    Section: Articles

    How to cite:
    Marconcini, S., Giammarinaro, E., Cosola, S., Genovesi, A., & Covani, U. (2019). Mandibular Osteonecrosis Associated with Antacid Therapy (Esomeprazole). European Journal of Case Reports in Internal Medicine, 6(10). https://doi.org/https://doi.org/10.12890/2019_001279