Mandibular Osteonecrosis Associated with Antacid Therapy (Esomeprazole)
  • Simone Marconcini
    Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Enrica Giammarinaro
    Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Saverio Cosola
    Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Anna Maria Genovesi
    Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy
  • Ugo Covani
    Tuscan Stomatologic Institute, Versilia General Hospital, Lido di Camaiore, Italy

Keywords

Mandibular osteonecrosis, antacid therapy, esomeprazole, osteonecrosis of the jaw, proton pump inhibitors

Abstract

Introduction: Osteonecrosis of the jaw has been consistently reported in the literature associated to the high-dose intravenous bisphosphonate therapy. However, osteonecrosis can also occur in patients who have other risk factors.
Case description: An unusual case of ONJ in a patient being treated with esomeprazole is reported.
Discussion: The probable association between proton pump inhibitor intake and osteonecrosis of the jaw should alert clinicians. Collaborations between medical and dental doctor and an early diagnosis might prevent or reduce the morbidity resulting from advanced destructive lesions of the jaw bone.

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    Published: 2019-10-14
    Issue: Vol 6 No 10 (view)


    How to cite:
    1.
    Marconcini S, Giammarinaro E, Cosola S, Genovesi AM, Covani U. Mandibular Osteonecrosis Associated with Antacid Therapy (Esomeprazole). EJCRIM 2019;6 doi:10.12890/2019_001279.

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