Cutaneous Vasculitis During Secukinumab Treatment
  • Camila da Silva Cendon Duran
    Hospital das Clínicas da Universidade de São Paulo, São Paulo, Brazil
  • Mittermayer Barreto Santiago
    Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil


Secukinumab is an inhibitor of interleukin IL-17A, and is mainly used in the treatment of psoriasis, psoriatic arthritis and ankylosing spondylitis. Although rarely, this drug may induce paradoxical reactions, such as cutaneous vasculitis. Worldwide, only four previous cases of vasculitis induced by secukinumab have been reported. We herein report the first case described in Brazil of cutaneous vasculitis due to secukinumab in a patient with peripheral spondyloarthritis who demonstrated good resolution after withdrawal of the drug and initiation of etanercept. Clinicians should be aware of this rare but potentially serious adverse effect of secukinumab.



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    Published: 2020-07-28
    Issue: 2020: Vol 7 No 10 (view)

    How to cite:
    Duran C da SC, Santiago MB. Cutaneous Vasculitis During Secukinumab Treatment. EJCRIM 2020;7 doi:10.12890/2020_001815.

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