Tracheobronchopathia Osteochondroplastica: Two Different Facets of a Rare Entity

  • Margarida Barata Pulmonology Department, Hospital Garcia de Orta, Almada, Portugal
  • Ricardo Gomes Pulmonology Department, Hospital Garcia de Orta, Almada, Portugal
  • Ana Catarina Moreira Pulmonology Department, Hospital Garcia de Orta, Almada, Portugal
  • Jorge Soares Pulmonology Department, Hospital Garcia de Orta, Almada, Portugal

Keywords

Rare diseases, pulmonology, tracheobronchopathia osteochondroplastica, bronchial fibroscopy

Abstract

Tracheobronchopathia osteochondroplastica (TBPO) is an uncommon benign disease, characterized by osseous or metaplastic cartilaginous nodules in the submucosa of the tracheobronchial tree. TBPO is easy to misdiagnose due to its non-specific clinical manifestation. We describe two cases of TBPO. The first patient was a 57-year-old woman with nocturnal dry cough and wheezing, in whom bronchoscopy revealed small diffuse mucosal irregularities involving the airway until the segmental bronchi. The other patient was a 69-year-old man with progressive worsening dyspnoea and productive cough presenting with severe stenosis of the trachea. Histological examination of both cases was consistent with TBPO. These cases highlight distinct forms of presentation of this rare entity.

VIEW THE ENTIRE ARTICLE

References

  • Lazor R, Cordier JF. Tracheobronchopathia osteochondroplastica. Orphanet Encyclopedia, June 2004. Available at: https://www.orpha.net/data/patho/GB/uk-TO.pdf (accessed 4 August 2020).
  • Leske V, Lazor R, Coetmeur D, Crestani B, Chatte G, Cordier JF. Tracheobronchopathia osteochondroplastica: a study of 41 patients. Medicine 2001;80(6):378–390.
  • Lundgren R, Stjernberg NL. Tracheobronchopathia osteochondroplastica. A clinical bronchoscopic and spirometric study. Chest 1981;80:706–709.
  • Ulasli SS, Kupeli E. Tracheobronchopathia osteochondroplastica: a review of the literature. Clin Respir J 2015;9(4):386–391.
  • Wilks S. Ossific deposits on larynx, trachea, and bronchi. Trans Pathol Soc London 1857;8:88.
  • Tukiainen H, Torkko M, Terho EO. Lung function in patients with tracheobronchopathia osteochondroplastica. Eur Resp J 1988;1(7):632–635.
  • Sun J, Xie L, Su X, Zhang X. Tracheobronchopathia osteochondroplastica: case report and literature review. Resp Med Case Rep 2015;15:14–17.
  • Devajara K, Sagar P, Chirom AS. Tracheobronchopathia osteochondroplastica: awareness is the key for diagnosis and management. BMJ Case Rep 2017:bcr-2017-220567.
  • Freitag L, Darwich K. Endoscopic treatment of tracheal stenosis. Thorac Surg Clin 2014;4:27–40.
  • Published: 2020-08-28

    Issue: Vol 7 No 11 (view)

    Section: Articles

    How to cite:
    1.
    Barata M, Gomes R, Moreira AC, Soares J. Tracheobronchopathia Osteochondroplastica: Two Different Facets of a Rare Entity. EJCRIM 2020;7 doi:10.12890/2020_001925.

    Similar Articles

    You may also start an advanced similarity search for this article.

    Most read articles by the same author(s)