Mesalazine-induced Hypersensitivity Pneumonitis
  • Ana Pereira
    Internal Medicine Department, Hospital Santa Maria Maior, Barcelos, Portugal
  • Cristina Marques
    Internal Medicine Department, Hospital Santa Maria Maior, Barcelos, Portugal
  • Teresa Boncoraglio
    Internal Medicine Department, Hospital Santa Maria Maior, Barcelos, Portugal
  • Joana Esteves
    Internal Medicine Department, Hospital Santa Maria Maior, Barcelos, Portugal
  • Marinha Silva
    Internal Medicine Department, Hospital Santa Maria Maior, Barcelos, Portugal
  • Joana Braga
    Internal Medicine Department, Hospital Santa Maria Maior, Barcelos, Portugal
  • Márcia Ribeiro
    Internal Medicine Department, Hospital Santa Maria Maior, Barcelos, Portugal

Keywords

Mesalazine, ulcerative colitis, drug reaction, hypersensitivity pneumonitis, lung injury

Abstract

A 57-year-old woman with Crohn's disease (ulcerative proctitis) treated with mesalazine (5-ASA) developed worsening respiratory distress and cough. The lack of response to antibiotics and the results of bronchoalveolar lavage led to the diagnosis of mesalazine-related hypersensitivity pneumonitis, an infrequent entity. Symptoms improved after discontinuation of mesalazine and the administration of corticosteroid therapy. The authors discuss the diagnosis and management of this rare condition.

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References

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    Published: 2021-01-07
    Issue: 2021: Vol 8 No 1 (view)


    How to cite:
    1.
    Pereira A, Marques C, Boncoraglio T, Esteves J, Silva M, Braga J, Ribeiro M. Mesalazine-induced Hypersensitivity Pneumonitis . EJCRIM 2021;8 doi:10.12890/2021_002194.

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