Fresh Frozen Plasma in Hereditary Angioedema Crisis: To Give or Not To Give?
  • Jamal Belkhouribchia
    Department of Internal Medicine and Endocrinology University Hospital Brussels
  • Sara Nguyen
    Department of Dermatology University Hospital Brussels, Belgium.


hereditary angioedema, fresh frozen plasma, C1-inhibitor, facial swelling


Objectives: Fresh frozen plasma (FFP) has been used in angioedema crises, however there is a risk of aggravating the symptoms as well as transmitting infections. In this report, the authors emphasize the dangers of this therapy.

Materials and methods: A 25-year-old woman with hereditary angioedema (HAE) was treated with FFP after which her symptoms escalated.

Results: Administration of purified C1-inhibitor (C1-INH) resulted in relief of her symptoms.

Conclusions: FFP is to be avoided in a HAE crisis. Newer therapies for angioedema are preferred.



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    Published: 2015-09-10
    Issue: Vol. 2 No. 5 (2015) (view)

    How to cite:
    Belkhouribchia J, Nguyen S. Fresh Frozen Plasma in Hereditary Angioedema Crisis: To Give or Not To Give?. EJCRIM 2015;2 doi:10.12890/2015_000253.