• Enes Erul
  Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey
• Gullu Sandal Uzun
  Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey https://orcid.org/0000-0002-5010-9114
• Deniz Koksal
  Department of Pulmonary Diseases, Faculty of Medicine, Hacettepe University, Ankara, Turkey https://orcid.org/0000-0001-8374-3691
• Onur Keskin
  Department of Gastroenterology, Faculty of Medicine, Hacettepe University, Ankara, Turkey https://orcid.org/0000-0002-9790-8204
• Serkan Uysal
  Department of Thoracic Surgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey https://orcid.org/0000-0002-1152-2854
• Ahmet Cagkan Inkaya
  Department of Infectious Diseases, Faculty of Medicine, Hacettepe University, Ankara, Turkey https://orcid.org/0000-0001-7943-8715
• Umut Kalyoncu
  Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey https://orcid.org/0000-0001-7129-2109

Keywords

Behçet's disease, infliximab, Budd–Chiari syndrome, vascular involvement, bronchopleural fistula

Abstract

Behçet's disease (BD) is multisystemic vasculitis with heterogeneous clinical manifestations. We describe the case of a 26-year-old man who presented with Budd–Chiari syndrome (BCS) related to BD. The patient received infliximab (IFX) due to the severity of vascular involvement. Subsequently, after IFX therapy, hospital-acquired pneumonia, trapped lung, and fungal infection of the lung and central nervous system developed as complications. The patient benefited from a second course of IFX and clinical remission was achieved following early identification and treatment of complications. Data on the presentation and prognosis of BCS related to BD are extremely limited. Our case report supports the growing evidence that anti-TNF antibody is a promising treatment for BD-related BCS.

Views: 486
HTML downloads: 101
PDF downloads: 365

Published: 2022-08-25
Issue: 2022: Vol 9 No 8 (view)