Deep vein thrombosis revealing a "silent" coeliac disease
  • Sofia Miranda
    Internal Medicine Department, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal
  • Patrícia Clara
    Internal Medicine Department, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal
  • Joana Rua
    Internal Medicine Department, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal
  • Miriam Cimbron
    Internal Medicine Department, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal
  • Fernando Salvador
    Internal Medicine Department, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal

Keywords

Venous thromboembolism, coeliac disease

Abstract

Introduction: We present a clinical case of a 45-year-old man with recurrent deep vein thrombosis (DVT) and multiple hospital admissions due to severe infectious conditions. A newfound hypoalbuminemia raised the suspicion of a protein-losing condition, with an upper endoscopy revealing lesions at the D2 level compatible with coeliac sprue and HLA typing positive for both DQ-2 and DQ-8.
Methods: A gluten free diet was started and apixaban was suspended.
Results: No new complications were reported.
Discussion: Multiple mechanisms are believed to be behind the association between DVT and coeliac disease. However, to this date, no consensus exists regarding the ideal duration of anticoagulation.

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    Published: 2023-08-18
    Issue: 2023: Vol 10 No 9 (view)

    How to cite:
    1.
    Miranda S, Clara P, Rua J, Cimbron M, Salvador F. Deep vein thrombosis revealing a "silent" coeliac disease. EJCRIM 2023;10 doi:10.12890/2023_003977.