Annular leukocytoclastic vasculitis: a new feature of IgA vasculitis
  • Nabil Belfeki
    Department of Internal Medicine and Clinical Immunology, Groupe Hospitalier Sud-Ile de France, Melun, France
  • Nouha Ghriss
    Department of Internal Medicine and Clinical Immunology, Groupe Hospitalier Sud-Ile de France, Melun, France
  • Sonia Kammoun
    Department of Internal Medicine and Clinical Immunology, Groupe Hospitalier Sud-Ile de France, Melun, France
  • Souheil Zayet
    Infectious Disease Department, Nord Franche-Comté Hospital, Trevenans, France
  • Cyrus Moini
    Department of Cardiology, Groupe Hospitalier Sud-Ile de France, Melun, France
  • Benjamin Terrier
    Department of Internal Medicine and Reference Centre of Rare Disease, Assistance Publique des Hôpitaux de Paris (AP-HP), Cochin Hospital, Paris, France

Keywords

Annular erythema, Ig-A mediated vasculitis, leukocytoclastic vasculitis, vasculitis, topical corticosteroids

Abstract

Background: Annular erythema is a rare manifestation of leukocytoclastic vasculitis. It may be associated with various drugs, infections, malignancies, or systemic diseases.
Case description: A 36-year-old woman with no personal medical history presented with annular erythema with target lesions and petechial purpura. The patient had fever and joint arthralgia. A skin biopsy showed leukocytoclastic vasculitis with IgA deposits on direct immunofluorescence. The diagnosis of immunoglobulin A vasculitis with annular leukocytoclastic vasculitis was made. The patient showed global improvement with topical steroids without relapse.
Conclusion: An annular variant of leukocytoclastic vasculitis is a rare manifestation of immunoglobulin A vasculitis.

VIEW THE ENTIRE ARTICLE

References

  • Trayes KP, Savage K, Studdiford JS. Annular lesions: diagnosis and treatment. Am Fam Physician 2018;98:283–291.
  • Maurelli M, Colato C, Gisondi P, Girolomoni G. Uncommon non-infectious annular dermatoses. Indian J Dermatol 2022;67:313.
  • Agnihotri G, Tsoukas MM. Annular skin lesions in infancy. Clin Dermatol 2022;40:505–512.
  • Meissner M, Beier C, Gille J, Kaufmann R. Annular leukocytoclastic vasculitis in association with chronic hepatitis B. J Eur Acad Dermatol Venereol 2007;21:135–136.
  • Cribier B, Cuny JF, Schubert B, Colson A, Truchetet F, Grosshans E. Recurrent annular erythema with purpura: a new variant of leucocytoclastic vasculitis responsive to dapsone. Br J Dermatol 1996;135:972–975.
  • Hong JS, Jin SP, Choi M, Lee KL, Lee JH, Cho S. Annular leukocytoclastic vasculitis in a patient with ulcerative colitis. Ann Dermatol 2011;23(Suppl 3):S338–S340.
  • Nousari HC, Kimyai-Asadi A, Stone JH. Annular leukocytoclastic vasculitis associated with monoclonal gammopathy of unknown significance. J Am Acad Dermatol 2000;43:955–957.
  • Nakajima H, Ikeda M, Yamamoto Y, Kodama H. Large annular purpura and paraneoplastic purpura in a patient with Sogren’s syndrome and cervical cancer. J Dermatol 2000;27:40–43.
  • Chiu C-S, Chang Y-C, Chung W-H, Yang L-J, Ho H-C, Chen M-J, et al. Annular leucocytoclastic vasculitis induced by chlorzoxazone. Br J Dermatol 2004;150:153.
  • Yasukawa K, Kato N, Hamasaka A, Hata H. Unusual annular purpura and erythema in a patient with malignant lymphoma accompanied with hyperglobulinemia. Int J Dermatol 2008;47:302–304.
  • Meissner M, Kaufmann R. Annular leukocytoclastic vasculitis after the administration of an amlodipine generic. J Eur Acad Dermatol Venereol 2009;23:238–239.
  • Chanprapaph K, Roongpisuthipong W, Thadanipon K. Annular leukocytoclastic vasculitis associated with anti-tuberculosis medications: a case report. J Med Case Rep 2013;7:34.
  • Matsuzaki Y, Jin K, Rokunohe A, Minakawa S, Nakano H, Sawamura D. Annular leukocytoclastic vasculitis associated with essential mixed cryoglobulinemia. Eur J Dermatol 2016;26:186–187.
  • Gambichler T, Susok L, Rached NA, Stucker M, Scheel C. Annular leukocytoclastic vasculitis in a patient with PR3-antineutrophil cytoplasmic antibody-positive ulcerative colitis. Eur J Dermatol 2020;30:420–421.
  • Cetinarslan T, Turel Ermertcan A, Aydogdu I, Temiz P. A rare vasculitis type in a patient with acute myeloblastic leukemia: annular leukocytoclastic vasculitis as a paraneoplastic syndrome? Dermatol Ther 2020;33:e14080.
  • Views: 21
    HTML downloads: 2
    PDF downloads: 23


    Published: 2024-04-03
    Issue: 2024: LATEST ONLINE (view)


    How to cite:
    1.
    Belfeki N, Ghriss N, Kammoun S, Zayet S, Moini C, Terrier B. Annular leukocytoclastic vasculitis: a new feature of IgA vasculitis. EJCRIM 2024;11 doi:10.12890/2024_004278.