Malignant Syphilis: A Rare Case of Early Secondary Syphilis in an Immunocompetent Patient
  • Ramiro Sá Lopes
    Centro Hospitalar Universitário do Algarve, Faro, Portugal
  • Ana Sara Monteiro
    Centro Hospitalar Universitário do Algarve, Faro, Portugal
  • Rosário Saez
    Centro Hospitalar Universitário do Algarve, Faro, Portugal
  • Carlos Candeias
    Centro Hospitalar Universitário do Algarve, Faro, Portugal
  • Catarina Mendonça
    Centro Hospitalar Universitário do Algarve, Faro, Portugal

Keywords

Early secondary syphilis, skin lesions, immunocompetent

Abstract

Early malignant syphilis is an uncommon form of secondary syphilis and characterized by pleomorphic multiple round-to-oval papules, some with necrosis, and associated with systemic signs and symptoms. Usually seen in immunosuppressed patients, mainly those infected with HIV, it can also be observed in immunocompetent patients.
We report a case in a young healthy woman with the characteristic features of the disease and with favourable skin lesion evolution after appropriate treatment with penicillin.

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References

  • Corti M, Solari R, De Carolis L, Figueiras O, Vittar N, Maronna E. Sífilis maligna en un paciente con infección por VIH. Presentación de un caso y revisión de la literatura. Rev Chilena Infectol 2012;29:678–681. doi: 10.4067/S0716-10182012000700017
  • Requena CB, Orasmo CR, Ocanha JP, Barraviera SR, Marques ME, Marques SA. Malignant syphilis in an immunocompetent female patient. An Bras Dermatol 2014 Nov-Dec;89(6):970–972. doi: 10.1590/abd1806-4841.20143155
  • Djawad K. Malignant syphilis as an initial presentation of HIV infection: a case report. Int J Dermatol Venereol 2021;4(3):192–194. doi: 10.1097/JD9.0000000000000162
  • Rao AG, Swathi T, Hari S, Kolli A, Reddy UD. Malignant syphilis in an immunocompetent adult male. Indian J Dermatol 2017;62(5):524–527. doi: 10.4103/ijd.IJD_733_16
  • Janier M, Unemo M, Dupin N, Tiplica G, Potocnik M, Patel R. 2020 European guideline on the management of syphilis. J Eur Acad Dermatol Venereol 2021;35:574–588. doi: 10.1111/jdv.16946
  • Ortigosa YM, Bendazzoli PS, Barbosa AM, Ortigosa LC. Early malignant syphilis. An Bras Dermatol 2016;91(5 Suppl 1):148–150. doi: 10.1590/abd1806-4841.20164491
  • Fustà-Novell X, Morgado-Carrasco D, Barreiro-Capurro A, Manzardo C, Alsina-Gibert M, et al. Syphilis maligna: a presentation to bear in mind [in English]. Actas Dermosifiliogr (Engl Ed) 2019;110(3):232–237. doi: 10.1016/j.ad.2018.02.024
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    Published: 2023-02-03
    Issue: 2023: Vol 10 No 1 (view)


    How to cite:
    1.
    Sá Lopes R, Monteiro AS, Saez R, Candeias C, Mendonça C. Malignant Syphilis: A Rare Case of Early Secondary Syphilis in an Immunocompetent Patient. EJCRIM 2023;10 doi:10.12890/2023_003712.

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