Mucosal Schwann cell hamartoma on screening colonoscopy: an unusual finding
  • Haidar Hussain Barjas
    Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar
  • Yousef Yahia
    Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar; Gastroenterology and Hepatology Department, Hamad Medical Corporation, Doha, Qatar
  • Joud Abuodeh
    Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar
  • Farah J.N. Assaf
    Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar
  • Adham Ammar
    Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar

Keywords

Hamartomas, Schwann cell, colonoscopy, polyps

Abstract

Schwann cells are found in the peripheral nervous system and can sometimes appear as benign hamartoma lesions in various parts of the body. Although rare in the gastrointestinal (GI) tract, they have been observed in the colon.
Recently, mucosal Schwann cell hamartomas of the GI tract have been studied, and it was discovered that they had yet to be investigated up to 2009. In this context, we present the case of a 60-year-old man who was found to have lesions in the transverse colon during a routine colonoscopy. No further investigations were conducted since these lesions have not been associated with any risk of malignancy transformation and have not been linked to any inherited syndromes.

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References

  • Gibson JA, Hornick JL. Mucosal Schwann cell “hamartoma”: clinicopathologic study of 26 neural colorectal polyps distinct from neurofibromas and mucosal neuromas. The Am J Surg Pathol 2009;33:781–787.
  • Salam S, Abosheaishaa H, Haseeb Ul Rasool M, Qasim N, Shahzad G. An unusual case of Schwann Cell Hamartoma in colon. Cureus 2023;15:e39301.
  • Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE. Association of Colonoscopy adenoma findings with long-term colorectal cancer incidence. JAMA 2018;319:2021–2031.
  • Winawer SJ, Fletcher RH, Miller L, Godlee F, Stolar MH, Mulrow CD, et al. Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology 1997;112:594–642. Erratum in: Gastroenterology 1997;112:1060. Erratum in: Gastroenterology 1998;114:625.
  • Strum WB. Colorectal adenomas. N Engl J Med 2016;374:1065–1075.
  • Bae MN, Lee JE, Bae SM, Kim EY, Kim EO, Jung SH, Oh JH, Min KO. Mucosal schwann-cell hamartoma diagnosed by using an endoscopic snare polypectomy. Ann Coloproctol 2013;29:130–134.
  • Ismael F, Khawar S, Hamza A. Mucosal Schwann cell hamartoma of the gallbladder. Autops Case Rep 2021;11:e2021338.
  • Pasquini P, Baiocchini A, Falasca L, Annibali D, Gimbo G, Pace F, et al. Mucosal Schwann cell “Hamartoma”: A new entity? World J Gastroenterol 2009;15:2287–2289.
  • Oguntuyo KY, Donnangelo LL, Zhu G, Ward S, Bhattacharaya A. A rare case of Schwann Cell Hamartoma in the duodenum. ACG Case Rep J 2022;9:e00894.
  • Rocco EG, Iannuzzi F, Dell’Era A, Falleni M, Moneghini L, Di Nuovo F, et al. Schwann cell hamartoma: case report. BMC Gastroenterol 2011;11:68.
  • Neis B, Hart P, Chandran V, Kane S. Mucosal schwann cell hamartoma of the colon in a patient with ulcerative colitis. Gastroenterol Hepatol (NY) 2013;9:183–185
  • Li Y, Beizai P, Russell JW, Westbrook L, Nowain A, Wang HL. Mucosal Schwann cell hamartoma of the gastroesophageal junction: A series of 6 cases and comparison with colorectal counterpart. Ann Diagn Pathol 2020;47:151531.
  • Chintanaboina J, Clarke K. Case of colonic mucosal Schwann cell hamartoma and review of literature on unusual colonic polyps. BMJ Case Rep 2018;2018:bcr2018224931.

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    Published: 2024-03-28
    Issue: 2024: LATEST ONLINE (view)

    How to cite:
    1.
    Barjas HH, Yahia Y, Abuodeh J, Assaf FJ, Ammar A. Mucosal Schwann cell hamartoma on screening colonoscopy: an unusual finding. EJCRIM 2024;11 doi:10.12890/2024_004461.