DOI: 10.12890/2017_000614

When Hypereosinophilia Leads to Stroke

Authors

  • Emilie Chalayer Intensive care unit, CHU Saint Etienne, Hopital Nord, 42055 Saint Etienne
  • Aude Pelissier Intensive care unit, CHU Saint Etienne, Hopital Nord, 42055 Saint Etienne
  • Bernard Tardy Clinical Investigation Center - CIC 1408, CHU Saint Etienne, France

emilie.chalayer@chu-st-etienne.fr

Keywords

Hypereosinophilia, stroke, cytomegalovirus, Loeffer endocarditis

Abstract

AFIP1L1-PDGFRA fusion can only be confirmed through molecular and cytogenetic investigations causing a delay in the diagnosis. However, patients with this mutation need urgent treatment because they present hypereosinophilia which may be associated with short-term tissue damage. Thromboembolism is a known cause of death in hypereosinophilic syndrome. A case of Loeffler endocarditis due to FIP1L1-PDGFRA-associated chronic eosinophilic leukemia presenting hemiparesis with fever, which also mislead the initial diagnosis, is reported.

View the entire article

Downloads

References

  1. Gotlib J. World Health Organization-defined eosinophilic disorders: 2015 update on diagnosis, risk stratification, and management. Am J Hematol/em> 2015;90:1077–89.
  2. Hyams C, Mabayoje DA, Copping R, Maranao D, Patel M, Labbett W, et al. Serological cross reactivity to CMV and EBV causes problems in the diagnosis of acute hepatitis E virus infection. J Med Virol 2014;86:478–83.
  3. Lioger B, Debiais S, Lauvin MA, Bonnaud I, Maillot F, Ferreira-Maldent N. Anticardiolipin antibodies-associated stroke in primary CMV infection. Eur J Neurol 2013;20:e105–6.

Published

2017-08-29

How to Cite

1.
Chalayer E, Pelissier A, Tardy B. When Hypereosinophilia Leads to Stroke. EJCRIM [Internet]. 2017 Aug. 29 [cited 2026 Nov. 3];4(6). Available from: https://www.ejcrim.com/index.php/EJCRIM/article/view/614