When Hypereosinophilia Leads to Stroke

  • Emilie Chalayer Intensive care unit, CHU Saint Etienne, Hopital Nord, 42055 Saint Etienne
  • Aude Pelissier Intensive care unit, CHU Saint Etienne, Hopital Nord, 42055 Saint Etienne
  • Bernard Tardy Clinical Investigation Center - CIC 1408, CHU Saint Etienne, France


Hypereosinophilia, stroke, cytomegalovirus, Loeffer endocarditis


AFIP1L1-PDGFRA fusion can only be confirmed through molecular and cytogenetic investigations causing a delay in the diagnosis. However, patients with this mutation need urgent treatment because they present hypereosinophilia which may be associated with short-term tissue damage. Thromboembolism is a known cause of death in hypereosinophilic syndrome. A case of Loeffler endocarditis due to FIP1L1-PDGFRA-associated chronic eosinophilic leukemia presenting hemiparesis with fever, which also mislead the initial diagnosis, is reported.



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  • Published: 2017-08-29

    Issue: Vol. 4 No. 6 (view)

    Section: Articles

    How to cite:
    Chalayer E, Pelissier A, Tardy B. When Hypereosinophilia Leads to Stroke. EJCRIM 2017;4 doi:10.12890/2017_000614.