Non-occlusive Mesenteric Ischaemia and Acute Kidney Injury: A Case Report of Severe Idiopathic Systemic Capillary Leak Syndrome
  • Cristina Pires Correia
    Internal Medicine Department, Centro Hospitalar São João, Porto, Portugal
  • Verónica Guiomar
    Internal Medicine Department, Centro Hospitalar São João, Porto, Portugal
  • Fátima Coelho
    Internal Medicine Department, Centro Hospitalar São João, Porto, Portugal
  • Jorge Almeida
    Internal Medicine Department, Centro Hospitalar São João, Porto, Portugal

Keywords

Idiopathic systemic capillary leak syndrome, ISCLS, hypovolaemic shock, monoclonal gammopathy of unknown significance, MGUS, non-occlusive mesenteric ischaemia, acute kidney injury

Abstract

Systemic capillary leak syndrome is a rare, underdiagnosed and life-threatening disease characterized by periodic episodes of hypovolaemic shock due to leakage of plasma from the intravascular to the extravascular space. It is associated with haemoconcentration, hypoalbuminaemia and generalized oedema.
We report the case of a patient with a history of emergent extensive small and large bowel resection and several episodes of hypovolaemic shock with acute renal injury, who presented with abdominal pain, headache and generalized oedema. Severe systemic capillary leak syndrome was diagnosed after a complex diagnostic approach. This case report describes the acute and prophylactic treatment administered to the patient and the 4-year follow-up. We highlight the importance of timely recognition and prompt treatment, as well as the need for new investigations to prevent the serious and unusual complications seen in this case.

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References

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    Published: 2019-06-24
    Issue: Vol 6 No 7 (view)

    How to cite:
    1.
    Correia CP, Guiomar V, Coelho F, Almeida J. Non-occlusive Mesenteric Ischaemia and Acute Kidney Injury: A Case Report of Severe Idiopathic Systemic Capillary Leak Syndrome. EJCRIM 2019;6 https://www.ejcrim.com/index.php/EJCRIM/article/view/1156.

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