Rapidly Progressive Bronchiectasis and Pulmonary Fibrosis in Yellow Nail Syndrome with Possible Association with Selective IgM Deficiency
  • Mohammad Abu-Abaa
    Internal Medicine, Capital Health Regional Medical Center, Trenton, NJ, USA
  • Mohamed Hassan
    Internal Medicine, Capital Health Regional Medical Center, Trenton, NJ, USA
  • Bashar Oudah
    Eisenhower Health, Rancho Mirage, CA, USA
  • Noor Al-Ameri
    Internal Medicine, Capital Health Regional Medical Center, Trenton, NJ, USA

Keywords

Yellow nail syndrome, bronchiectasis, pulmonary fibrosis, lymphoedema

Abstract

A 67-year-old man with a history of IgM deficiency and pulmonary fibrosis and bronchiectasis was admitted for management of worsening symptoms. Investigations revealed exudative pleural effusion with rapidly progressive bronchiectasis. Although a potential trigger of bronchiectasis and pulmonary fibrosis was not identified despite extensive work-up by several physicians in the past, a bedside observation of yellow dystrophic nails on all extremities revealed the diagnosis. This case report helps to remind clinicians of a rare medical disorder of still uncertain aetiology and no available cure. This case is consistent with a few previous case reports that suggest a potential association with selective immunoglobulin deficiency.

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    Published: 2022-09-27
    Issue: 2022: Vol 9 No 9 (view)

    How to cite:
    1.
    Abu-Abaa M, Hassan M, Oudah B, Al-Ameri N. Rapidly Progressive Bronchiectasis and Pulmonary Fibrosis in Yellow Nail Syndrome with Possible Association with Selective IgM Deficiency. EJCRIM 2022;9 doi:10.12890/2022_003577.