Salmonella osteomyelitis of unknown origin: an underestimated infection
  • Victor Rentmeister
    Service des Urgences, CHC Clinique MontLégia, Liège, Belgium
  • Noel Lorenzo-Villalba
    Service de Médecine Interne, Hôpitaux Universitaires de Strasbourg, Strasbourg, France
  • Yilmaz Gorur
    Service de Radiologie, Clinique André Renard, Herstal, Belgium
  • Michele Yerna
    Service des Urgences, CHC Clinique MontLégia, Liège, Belgium
  • Deeba Ali
    Service des Urgences, CHC Clinique MontLégia, Liège, Belgium


Salmonella osteomyelitis, MRI, bone lesion


Salmonella osteomyelitis is an underdiagnosed pathology with unusual clinical presentations. The patient was a 24-year-old female with no previous medical history who presented to the emergency department with progressive pain in the left arm for several months.
She was initially treated unsuccessful with augmentin for 7 days for suspicious cellulites. Standard elbow X-rays described a lesion initially considered as metastatic. Investigations were completed with magnetic resonance imaging (MRI) compatible with osteomyelitis. Following surgical sampling, salmonella enterica infection was diagnosed. The patient recovered full use of her limb after 8 days of IV antibiotic therapy with third-generation cephalosporin, and she completed 11 weeks of antibiogram-targeted PO fluoroquinolone therapy. Salmonella osteomyelitis could mimic other diseases, making diagnosis difficult.



  • Huang Z-D, Wang C-X, Shi T-B, Wu B-J, Chen Y, Li W-B, et al. Salmonella osteomyelitis in adults: a systematic review. Orthop Surg 2021;13:1135–1140.
  • McAnearney S, McCall D. Salmonella osteomyelitis. Ulster Med J 2015;84:171–172.
  • Maffulli N, Papalia R, Zampogna B, Torre G, Albo E, Denaro V. The management of osteomyelitis in the adult. Surgeon 2016;14:345–360.
  • Rohilla R, Bhatia M, Gupta P, Singh A, Shankar R, Omar BJ. Salmonella osteomyelitis: a rare extraintestinal manifestation of an endemic pathogen. J Lab Physicians 2019;11:164–170.
  • Dym H, Zeidan J. Microbiology of acute and chronic osteomyelitis and antibiotic treatment. Dent Clin North Am 2017;61:271–282.
  • Views: 381
    HTML downloads: 76
    PDF downloads: 217

    Published: 2023-10-18
    Issue: 2023: Vol 10 No 11 (view)

    How to cite:
    Rentmeister V, Lorenzo-Villalba N, Gorur Y, Yerna M, Ali D. Salmonella osteomyelitis of unknown origin: an underestimated infection. EJCRIM 2023;10 doi:10.12890/2023_004092.

    Most read articles by the same author(s)

    << < 1 2