Primary pulmonary T-cell lymphoma mimicking asthma and community-acquired pneumonia: a rare case report
  • Khoa Nguyen-Dang
    Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam; Department of Pulmonary Medicine, Cho Ray Hospital, Ho Chi Minh City, Vietnam
  • Nguyen Tran-Ngoc
    Department of Tuberculosis and Pulmonary Disease, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam
  • Ngoc Duong-Minh
    Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam; Department of Pulmonary Medicine, Cho Ray Hospital, Ho Chi Minh City, Vietnam
  • Thong Pham-Quang
    Department of Pathology, Cho Ray Hospital, Ho Chi Minh City, Vietnam
  • Hanh-Duyen Bui-Thi
    Department of Intensive Care, University Medical Center Ho Chi Minh City, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam

Keywords

Primary pulmonary T-cell lymphoma, asthma, CT angiogram sign, non-resolving pneumonia

Abstract

Primary pulmonary T-cell lymphoma (PPTL) is a rare disease. Diagnosing PPTL is challenging due to non-specific clinical symptoms and imaging. A 32-year-old female presented with persistent fever, cough, and dyspnoea. The symptoms were initially treated as asthma and community-acquired pneumonia without improvement. Chest computed tomography (CT) revealed bilateral consolidations with a CT angiogram sign, and flexible bronchoscopy showed infiltrative lesions causing bronchial stenosis. Histopathological examination of the tissue biopsy identified T-cell lymphoma through immunohistochemical staining positive for CD3. This case highlights the importance of considering differential diagnoses such as PPTL in patients with atypical presentations of asthma or non-resolving pneumonia. This case also demonstrates the diagnostic utility of flexible bronchoscopy in identifying airway obstruction due to malignant cells, which can mimic asthma.

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    Published: 2023-11-20
    Issue: 2023: Vol 10 No 12 (view)


    How to cite:
    1.
    Nguyen-Dang K, Tran-Ngoc N, Duong-Minh N, Pham-Quang T, Bui-Thi H-D. Primary pulmonary T-cell lymphoma mimicking asthma and community-acquired pneumonia: a rare case report. EJCRIM 2023;10 doi:10.12890/2023_004182.

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