A rare case of an elderly male with progression to chronic myeloid leukaemia secondary to chronic lymphocytic leukaemia
  • Sakditad Saowapa
    Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Watsachon Pangkanon
    Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Yaw Adu
    School of Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Nattanicha Chaisrimaneepan
    Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Diego Olavarria Bernal
    Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA
  • Natchaya Polpichai
    Department of Internal Medicine, Louis A Weiss Memorial Hospital, Chicago, USA
  • Pharit Siladech
    Internal Medicine Department, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Jasmine Sekhon
    Department of Hematology and Oncology, Texas Tech University Health Sciences Center, Lubbock, USA

Keywords

Coexisting CLL/CML, chronic lymphocytic leukaemia, chronic myeloid leukaemia, dasatinib

Abstract

Chronic lymphocytic leukaemia (CLL) is a lymphoproliferative disorder characterised by an accumulation of monoclonal B lymphocytes, with an increased risk of secondary cancers. The coexistence of CLL and chronic myeloid leukaemia (CML) is a rare phenomenon, with three main types being classified: CML preceding CLL, CLL preceding CML and simultaneous occurrence. The coexistence of these chronic leukaemias poses a complex clinical challenge, with the underlying mechanisms of their association remaining enigmatic. Here, we present a report of an elderly male with a long history of CLL, who was subsequently diagnosed with secondary CML.

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    Published: 2024-03-01
    Issue: 2024: Vol 11 No 4 (view)


    How to cite:
    1.
    Saowapa S, Pangkanon W, Adu Y, Chaisrimaneepan N, Olavarria Bernal D, Polpichai N, Siladech P, Sekhon J. A rare case of an elderly male with progression to chronic myeloid leukaemia secondary to chronic lymphocytic leukaemia. EJCRIM 2024;11 doi:10.12890/2024_004297.

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