A Case of Spontaneous Regression of Pulmonary Small Cell Carcinoma

  • Motoi Ugajin Department of Respiratory Medicine, Nagoya Tokushukai General Hospital, Japan
  • Hisanori Kani Department of Thoracic Surgery, Nagoya Tokushukai General Hospital, Japan

Keywords

Spontaneous regression, pulmonary small cell carcinoma, T lymphocyte-mediated immunity, atrial natriuretic peptide

Abstract

An 82-year-old man was examined using chest computed tomography after treatment for pneumonia. Imaging showed a nodular shadow in the left lower lobe with associated enlarged lymph nodes. A polypoid tumour was observed on bronchoscopic examination, and the histological findings showed pulmonary small cell carcinoma with infiltration of CD3-positive and CD8-positive lymphocytes. The patient declined any antitumoural therapy and experienced an exacerbation of heart failure treated with atrial natriuretic peptide. Eighteen months after the diagnosis, the polypoid tumour had disappeared. T lymphocyte-mediated immunity and the antitumoural effects of atrial natriuretic peptide may have influenced the observed spontaneous regression.

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  • Published: 2019-07-31

    Issue: Vol 6 No 8 (view)

    Section: Articles

    How to cite:
    Ugajin, M., & Kani, H. (2019). A Case of Spontaneous Regression of Pulmonary Small Cell Carcinoma. European Journal of Case Reports in Internal Medicine, 6(8). https://doi.org/https://doi.org/10.12890/2019_001203