Testicular Adrenal Rest Tumour (TART) or Testicular Malignancy: A Clinical Dilemma
  • Moni Roy
    Department of Internal Medicine, University of Illinois College of Medicine at Peoria and OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Ashish Kumar Roy
    Department of Internal Medicine, University of Illinois College of Medicine at Peoria and OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Tulika Chatterjee
    Department of Internal Medicine, University of Illinois College of Medicine at Peoria and OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Saurabh Bansal
    Department of Internal Medicine, University of Illinois College of Medicine at Peoria and OSF Saint Francis Medical Center, Peoria, Illinois, USA

Keywords

Testicular adrenal rest tumour,, congenital adrenal insufficiency

Abstract

Testicular adrenal rest tumour (TART) is a known entity in patients with congenital adrenal hyperplasia. An adult patient presenting with testicular enlargement raises a concern for malignancy and this creates a diagnostic dilemma between non-malignant conditions such as TART versus testicular malignancy. We describe a case where the patient underwent orchiectomy due to clinical concern for malignancy but, retrospectively, this outcome could have been prevented by medical treatment. This case emphasises the need to learn from errors. There is a need to increase awareness of the condition among medical professionals to reduce the chances of unnecessary surgical intervention.

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References

  • Claahsen-van der Grinten HL, Otten BJ, Stikkelbroeck MM, Sweep FC, Hermus AR. Testicular adrenal rest tumours in congenital adrenal hyperplasia. Best Pract Res Clin Endocrinol Metab 2009;23:209–220.

  • Mazzilli R, Stigliano A, Delfino M, Olana S, Zamponi V, Iorio C, et al. The high prevalence of testicular adrenal rest tumors in adult men with congenital adrenal hyperplasia is correlated with ACTH levels. Front Endocrinol (Lausanne) 2019;10:335.

  • Engels M, Span PN, van Herwaarden AE, Sweep FCGJ, Stikkelbroeck NMML, Claahsen-van der Grinten HL. Testicular adrenal rest tumors: current insights on prevalence, characteristics, origin, and treatment. Endocr Rev 2019;40(4):973–987.

  • Rajkanna J, Oyibo SO. Large testicular adrenal rest tumours in a patient with congenital adrenal hyperplasia. Endocrinol Diabetes Metab Case Rep 2015;2015:140080.

  • Cabrera MS, Vogiatzi MG, New MI. Long term outcome in adult males with classic congenital adrenal hyperplasia. J Clin Endocrinol Metabol 2001;86(7):3070–3078.

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    Published: 2020-05-08
    Issue: 2020: Vol 7 No 8 (view)

    How to cite:
    1.
    Roy M, Roy AK, Chatterjee T, Bansal S. Testicular Adrenal Rest Tumour (TART) or Testicular Malignancy: A Clinical Dilemma. EJCRIM 2020;7 doi:10.12890/2020_001669.

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