COVID-19-related Multisystem Inflammatory Syndrome in a Young Adult
  • Francisco Pombo
    Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal
  • Carolina Seabra
    Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal
  • Vergílio Soares
    Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal
  • Ana João Sá
    Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal
  • Inês Ferreira
    Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal
  • Marina Mendes
    Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal

Keywords

COVID-19, multisystem inflammatory syndrome, adult

Abstract

Introduction: A condition called multisystem inflammatory syndrome in children (MIS-C), related to past SARS-CoV-2 infection, has been described in a series of cases. There is a growing body of evidence suggesting a similar entity in adults (MIS-A). We report a case of a young adult with a hyperinflammatory systemic syndrome with end-organ lesions and a recent SARS-CoV-2 infection.

Methods and Procedures: The patient developed end-organ lesions in the respiratory, cardiovascular, digestive, haematological and mucocutaneous systems. A wide diagnostic work-up did not find any specific aetiology (autoimmunity, neoplastic or infectious). There was evidence of past SARS-CoV-2 infection with positive autoimmune titres (positive IgG). A presumptive diagnosis of MIS-A was made and treatment with corticosteroids was introduced with improvement.

Discussion: COVID-19-related multisystem inflammatory syndrome in adults is still an unknown entity with no diagnostic criteria or treatment guidelines. Much of what is known is inferred from what we already know about MIS-C. There have been several reported cases with severity ranging from mild to severe. The mechanisms behind this condition are still largely unknown. More evidence is needed to establish diagnosis and treatment.

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References

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    Published: 2021-04-19
    Issue: 2021: Vol 8 No 4 (view)

    How to cite:
    1.
    Pombo F, Seabra C, Soares V, Sá AJ, Ferreira I, Mendes M. COVID-19-related Multisystem Inflammatory Syndrome in a Young Adult. EJCRIM 2021;8 doi:10.12890/2021_002520.

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